: a crystalline alkaloid compound C8H7N that is a decomposition product of proteins containing tryptophan, that can be made synthetically, and that is used in perfumes
also : a derivative of indole

Examples of indole in a Sentence

Recent Examples on the Web
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As part of the testing, the team discovered the enzyme can turn the organic compound indole to indigo. — Sarah Jones, Footwear News, 5 June 2026 Compounds known as indoles, found in vegetables from the cabbage family such as broccoli, cabbage and cauliflower, can activate Treg cells and help prevent gut inflammation. — Mitzi Nagarkatti, The Conversation, 10 Oct. 2025 This transition is accompanied by exposure to breast milk, which contains microbes capable of producing indoles. — Jenny Lehmann, Discover Magazine, 7 Feb. 2025

Word History

Etymology

International Scientific Vocabulary ind- + -ole

First Known Use

1869, in the meaning defined above

Time Traveler
The first known use of indole was in 1869

Browse Nearby Words

Cite this Entry

“Indole.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/indole. Accessed 24 Sep. 2026.

Medical Definition

: a crystalline compound C8H7N that is found along with skatole in the intestines and feces as a decomposition product of proteins containing tryptophan and that can be made synthetically
also : a derivative of indole

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