hypersensitive

adjective

hy·​per·​sen·​si·​tive ˌhī-pər-ˈsen(t)-s(ə-)tiv 

1

: excessively or abnormally sensitive

2

: abnormally susceptible physiologically to a specific agent (such as a drug or antigen)

hypersensitiveness noun

hypersensitivity

ˌhī-pər-ˌsen(t)-sə-ˈti-və-tē 

noun

Examples of hypersensitive in a Sentence

She's hypersensitive about her past.

People who are hypersensitive to the chemical may have violent reactions even to small amounts.

Recent Examples on the Web

Blurry vision, a stiff neck, hypersensitive skin, numbness and weakness that would come and go. — Erika Edwards, NBC news, 13 Aug. 2026

Adam gets off on being asphyxiated, while Ingeborg has hypersensitive fingertips to the extent of them effectively being her erogenous zone; gracing her hands against the fabric that’s wrapped her lover during his orgasm seems to set off her own. — Josh Slater-Williams, IndieWire, 11 Aug. 2026

Studies also suggest that individuals with migraine are more susceptible to brain freeze, probably because the trigeminal nerve and its associated pain pathways are already hypersensitive. — Encyclopedia Britannica, 7 Aug. 2026

My own favorite album is Huntington Ashram Monastery—split equally between piano and harp, with the note-perfect complement of Ron Carter’s hypnotic double bass and Rashied Ali’s hypersensitive drums. — Ian Penman, Harpers Magazine, 4 Aug. 2026

Word History

First Known Use

1871, in the meaning defined at sense 1

Rhymes for hypersensitive

• photosensitive
• insensitive
• radiosensitive
• sensitive

Kids Definition

hypersensitive

adjective

hy·​per·​sen·​si·​tive ˌhī-pər-ˈsen(t)-sət-iv 

-ˈsen(t)-stiv

: very sensitive especially to an abnormal degree

hypersensitiveness noun

Medical Definition

hypersensitive

adjective

hy·​per·​sen·​si·​tive ˌhī-pər-ˈsen(t)-sət-iv, -ˈsen(t)-stiv 

1

: excessively or abnormally sensitive

2

: abnormally susceptible physiologically to a specific agent (as a drug or antigen)

hypersensitiveness noun

hypersensitivity

-ˌsen(t)-sə-ˈtiv-ət-ē 

noun

plural hypersensitivities