hy·​per·​acute ˌhī-pər-ə-ˈkyüt How to pronounce hyperacute (audio)
variants or hyper-acute
: extremely or excessively acute
a hyperacute sensitivity to light
… the problem of hyperacute rejection—a violent immune response that can destroy a transplanted organ in minutes …Arlene Judith Klotzko

Examples of hyperacute in a Sentence

Recent Examples on the Web Some edits disabled three genes involved in hyperacute rejection, which occurs minutes after a transplant when the recipient’s immune system recognizes the new organ as foreign. Emily Mullin, WIRED, 11 Oct. 2023 Everything that’s matchless about Raban’s work — his hyperacute eye for detail, his powers of synthesis, his mordant sense of humor, his vast reservoirs of knowledge and his love of travel — is there. Mary Ann Gwinn, Los Angeles Times, 19 Sep. 2023 Newton is a logical thinker and a hyperacute observer, with a prodigious memory and a lacerating honesty. Mary Ann Gwinn, Los Angeles Times, 24 Mar. 2022 In hyperacute rejection, large blood clots rapidly form, obstructing the blood supply of the donor organ. Rivka Galchen, The New Yorker, 21 Feb. 2022 The first and most dangerous hurdle is hyperacute rejection. Megan Molteni, STAT, 24 Jan. 2022 The transplantation itself went smoothly: the kidneys showed no signs of hyperacute rejection and even began to function. Joanna Thompson, Scientific American, 20 Jan. 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'hyperacute.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1823, in the meaning defined above

Time Traveler
The first known use of hyperacute was in 1823

Dictionary Entries Near hyperacute

Cite this Entry

“Hyperacute.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hyperacute. Accessed 24 Jul. 2024.

Medical Definition


hy·​per·​acute ˌhī-pə-rə-ˈkyüt How to pronounce hyperacute (audio)
: extremely or excessively acute
hyperacute hearing
And the problem of hyperacute rejection—a violent immune response that can destroy a transplanted organ in minutes—seems to have been solved for pig organs.Arlene Judith Klotzko, Scientific American

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