hy·​droxy·​pro·​line hī-ˌdräk-sē-ˈprō-ˌlēn How to pronounce hydroxyproline (audio)
: an amino acid C5H9NO3 that occurs naturally as a constituent of collagen

Example Sentences

Recent Examples on the Web The collagen molecule is made up of three amino acids: glycine, proline, and hydroxyproline. Amber Smith, Discover Magazine, 23 Mar. 2022 The star ingredient - soy proteins - are rich in the amino acid hydroxyproline, which is known to improve elasticity and smooth skin to promote a healthy-looking complexion. Grooming Playbook, The Salt Lake Tribune, 13 May 2022 The salon and nail-care brand Tenoverten created a restorative hand cream with a formula that, thanks to its proprietary blend of five oils, not only locks in moisture but also builds collagen and brightens skin using hydroxyproline and Kakadu plum. Caitie Kelly, New York Times, 19 Mar. 2020 The supplements specifically contain high amounts of three amino acids that are key building blocks for collagen synthesis in the body: glycine, proline and hydroxyproline. Lisa Drayer, CNN, 17 Oct. 2019 But one method, called HYP, extracted and purified a sample of a single amino acid, hydroxyproline, from the collagen sample. Kiona N. Smith, Ars Technica, 18 June 2018 The collagen found in our bodies is made up of several amino acids, including glycine, proline, hydroxyproline, and arginine. Elise Deming, Rdn, Ldn, Philly.com, 26 Feb. 2018 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'hydroxyproline.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

First Known Use

1905, in the meaning defined above

Time Traveler
The first known use of hydroxyproline was in 1905

Dictionary Entries Near hydroxyproline

Cite this Entry

“Hydroxyproline.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hydroxyproline. Accessed 7 Feb. 2023.

Medical Definition


hy·​droxy·​pro·​line -ˈprō-ˌlēn How to pronounce hydroxyproline (audio)
: an amino acid C5H9NO3 that occurs naturally as a constituent of collagen

More from Merriam-Webster on hydroxyproline

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

The Great British Vocabulary Quiz

  • union jack speech bubble
  • Named after Sir Robert Peel, what are British police called?
Spell It

Hear a word and type it out. How many can you get right?

Solve today's spelling word game by finding as many words as you can with using just 7 letters. Longer words score more points.

Can you make 12 words with 7 letters?