hydroxyproline

noun

hy·​droxy·​pro·​line hī-ˌdräk-sē-ˈprō-ˌlēn 

: an amino acid C₅H₉NO₃ that occurs naturally as a constituent of collagen

Examples of hydroxyproline in a Sentence

Recent Examples on the Web

Your body breaks it down into amino acids, primarily glycine, proline, and hydroxyproline. — Jillian Kubala, Health, 4 June 2026

In the new study, researchers aimed to turn things around by targeting hydroxyproline — an amino acid present in mammalian collagen — that was drawn from a sample of the Lapedo child’s right radius. — Jack Knudson, Discover Magazine, 10 Mar. 2025

To determine the child’s age, scientists extracted a specific amino acid called hydroxyproline from collagen in the bones. — Sarah Kuta, Smithsonian Magazine, 10 Mar. 2025

The star ingredient - soy proteins - are rich in the amino acid hydroxyproline, which is known to improve elasticity and smooth skin to promote a healthy-looking complexion. — Grooming Playbook, The Salt Lake Tribune, 13 May 2022

Glycine helps to stabilize the collagen molecule, proline promotes collagen formation, and hydroxyproline is necessary for the correct structure of collagen fibers. — Amber Smith, Discover Magazine, 23 Mar. 2022

Word History

First Known Use

1905, in the meaning defined above

Rhymes for hydroxyproline

• aminophylline
• azathioprine
• cholestyramine
• cryptocrystalline
• intercrystalline
• microcrystalline
• monocrystalline
• nanocrystalline
• neuroendocrine
• phthalocyanine
• polycrystalline
• aconitine

Medical Definition

hydroxyproline

noun

hy·​droxy·​pro·​line -ˈprō-ˌlēn 

: an amino acid C₅H₉NO₃ that occurs naturally as a constituent of collagen