hydrochlorothiazide

noun

hy·​dro·​chlo·​ro·​thi·​a·​zide ˌhī-drə-ˌklȯr-ə-ˈthī-ə-ˌzīd 

: a diuretic and antihypertensive drug C₇H₈ClN₃O₄S₂

Examples of hydrochlorothiazide in a Sentence

Recent Examples on the Web

Common types include thiazide diuretics (like chlorthalidone or hydrochlorothiazide) and loop diuretics (like torsemide or Lasix). —Karen Berger, Verywell Health, 9 Dec. 2025

Bisoprolol fumarate and hydrochlorothiazide tablets made by Glenmark Pharmaceuticals may contain trace amounts of a cholesterol medication. —Jenna Anderson, Health, 9 Dec. 2025

Examples of diuretic medication include hydrochlorothiazide or furosemide. —Michael Schuh Pharm.d., Anchorage Daily News, 2 Sep. 2023

And it was probably triggered by his hydrochlorothiazide. —Lisa Sanders, M.d., New York Times, 6 July 2023

Diuretics like chlorthalidone or hydrochlorothiazide can deplete the body of potassium, magnesium and even sodium. —Joe Graedon, M.s., and Teresa Graedon, Ph.d., oregonlive, 6 Mar. 2023

Aurobindo Pharma USA is recalling two lots of quinapril and hydrochlorothiazide tablets due to levels of nitrosamine. —Natalie Neysa Alund, USA TODAY, 27 Oct. 2022

Accuretic is a combination of two different drugs: quinapril and hydrochlorothiazide. —Sophie Mellor, Fortune, 23 Mar. 2022

Word History

Etymology

hydr- + chlor- + thiazine + -ide

First Known Use

1958, in the meaning defined above

Rhymes for hydrochlorothiazide

• lipopolysaccharide
• mucopolysaccharide
• oligonucleotide
• abide
• allied
• applied
• aside
• astride
• azide
• backside
• bankside
• bastide

Medical Definition

hydrochlorothiazide

noun

hy·​dro·​chlo·​ro·​thi·​a·​zide -ˌklōr-ə-ˈthī-ə-ˌzīd, -ˌklȯr- 

: a diuretic and antihypertensive drug C₇H₈ClN₃O₄S₂

—abbreviation HCTZ

Note: Trademarks for preparations containing hydrochlorothiazide include Benicar HCT, Dyazide, Hyzaar, Maxzide, and Tribenzor.