hy·​dro·​chlo·​ro·​thi·​a·​zide ˌhī-drə-ˌklȯr-ə-ˈthī-ə-ˌzīd How to pronounce hydrochlorothiazide (audio)
: a diuretic and antihypertensive drug C7H8ClN3O4S2

Examples of hydrochlorothiazide in a Sentence

Recent Examples on the Web Examples of diuretic medication include hydrochlorothiazide or furosemide. Michael Schuh Pharm.d., Anchorage Daily News, 2 Sep. 2023 And it was probably triggered by his hydrochlorothiazide. Lisa Sanders, M.d., New York Times, 6 July 2023 Diuretics like chlorthalidone or hydrochlorothiazide can deplete the body of potassium, magnesium and even sodium. Joe Graedon, M.s., and Teresa Graedon, Ph.d., oregonlive, 6 Mar. 2023 Accuretic is a combination of two different drugs: quinapril and hydrochlorothiazide. Sophie Mellor, Fortune, 23 Mar. 2022 Aurobindo Pharma USA is recalling two lots of quinapril and hydrochlorothiazide tablets due to levels of nitrosamine. Natalie Neysa Alund, USA TODAY, 27 Oct. 2022 In the case of hydrochlorothiazide (HCTZ), a common diuretic, the result can be low sodium and low potassium levels. Dr. Keith Roach, oregonlive, 12 July 2022 Quinapril is an angiotensin-converting enzyme (ACE) inhibitor that prevents blood vessels from narrowing, while hydrochlorothiazide is a diuretic, which causes a person to urinate more and flushes out sodium in the body. Sophie Mellor, Fortune, 23 Mar. 2022 For a person in their 70s with mild high blood pressure and no other conditions, there are many good choices, but a low-dose diuretic such as hydrochlorothiazide is a very good, low-cost choice. Dr. Keith Roach, oregonlive, 15 Mar. 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'hydrochlorothiazide.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


hydr- + chlor- + thiazine + -ide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of hydrochlorothiazide was in 1958

Dictionary Entries Near hydrochlorothiazide

Cite this Entry

“Hydrochlorothiazide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hydrochlorothiazide. Accessed 15 Jun. 2024.

Medical Definition


hy·​dro·​chlo·​ro·​thi·​a·​zide -ˌklōr-ə-ˈthī-ə-ˌzīd, -ˌklȯr- How to pronounce hydrochlorothiazide (audio)
: a diuretic and antihypertensive drug C7H8ClN3O4S2
abbreviation HCTZ

Note: Trademarks for preparations containing hydrochlorothiazide include Benicar HCT, Dyazide, Hyzaar, Maxzide, and Tribenzor.

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