hormone replacement therapy

noun

: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy
The usual treatment for hypothyroidism is hormone replacement therapy.Kate Murphy
especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis
abbreviation HRT

Examples of hormone replacement therapy in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Last month, Schumer opened up about her experience undergoing hormone replacement therapy for perimenopause as well as using weight-loss medication. Desiree Anello, PEOPLE, 20 Apr. 2026 For more than 20 years, the warning has kept many women away from hormone replacement therapy after a 2002 Women’s Health Initiative study linked it to a higher risk of breast cancer, heart attacks and strokes in postmenopausal women. Laura Trujillo, USA Today, 17 Apr. 2026 They were also asked to select and rank the helpfulness of 15 symptom management strategies, such as masturbating, exercising, maintaining a healthy diet and using hormone replacement therapy (HRT), based on how much relief each provided. Helen Carefoot, Flow Space, 10 Apr. 2026 The patches are a type of hormone replacement therapy that delivers estrogen directly through the skin into the ​bloodstream. Reuters, NBC news, 9 Apr. 2026 See All Example Sentences for hormone replacement therapy

Word History

First Known Use

1945, in the meaning defined above

Time Traveler
The first known use of hormone replacement therapy was in 1945

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Cite this Entry

“Hormone replacement therapy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hormone%20replacement%20therapy. Accessed 24 Apr. 2026.

Medical Definition

hormone replacement therapy

noun
: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy
The usual treatment for hypothyroidism is hormone replacement therapy.Kate Murphy
especially : the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis
abbreviation HRT

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