hormone replacement therapy
noun
: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy
The usual treatment for hypothyroidism is hormone replacement therapy.—
Kate Murphy
Kate Murphy
especially
: the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis
—abbreviation HRT
Examples of hormone replacement therapy in a Sentence
Recent Examples on the Web
The most prescribed care option for menopause worldwide is hormone therapy, also known as hormone replacement therapy or HRT, which works by replacing the hormones that have decreased inside the body.
—Sashikala Vp, CNN Money, 4 Dec. 2025
Back then, she was advised against hormone replacement therapy because her own mother had had breast cancer.
—Lauren Pastrana, CBS News, 4 Dec. 2025
Some outstanding questions remain, including how long women would need to stay on hormone replacement therapy or whether estrogen would be more protective for women with a genetic predisposition to Alzheimer’s.
—Akshay Syal, NBC news, 27 Nov. 2025
In her new role with Midi Health, Fadal will use her platform to increase awareness around perimenopause and menopause, as well as highlight Midi Health’s resources spanning care, prescriptions like hormone replacement therapy and its new line of supplements.
—Emily Burns, Footwear News, 18 Nov. 2025
See All Example Sentences for hormone replacement therapy
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Sashikala Vp, CNN Money, 4 Dec. 2025
Back then, she was advised against hormone replacement therapy because her own mother had had breast cancer.
—Lauren Pastrana, CBS News, 4 Dec. 2025
Some outstanding questions remain, including how long women would need to stay on hormone replacement therapy or whether estrogen would be more protective for women with a genetic predisposition to Alzheimer’s.
—Akshay Syal, NBC news, 27 Nov. 2025
In her new role with Midi Health, Fadal will use her platform to increase awareness around perimenopause and menopause, as well as highlight Midi Health’s resources spanning care, prescriptions like hormone replacement therapy and its new line of supplements.
—Emily Burns, Footwear News, 18 Nov. 2025
See All Example Sentences for hormone replacement therapy
Cite this Entry
“Hormone replacement therapy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hormone%20replacement%20therapy. Accessed 20 Dec. 2025.
Copy CitationMedical Definition
hormone replacement therapy
noun
: the therapeutic use of hormones typically to increase diminished levels in the body : hormone therapy
The usual treatment for hypothyroidism is hormone replacement therapy.—Kate Murphy
Kate Murphy
especially
: the administration of estrogen often along with a synthetic progestin especially to ameliorate the symptoms of menopause and reduce the risk of postmenopausal osteoporosis
—abbreviation HRT
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