histoplasmosis

noun

his·​to·​plas·​mo·​sis ˌhi-stə-plaz-ˈmō-səs How to pronounce histoplasmosis (audio)
: a respiratory disease with symptoms like those of influenza that is caused by a fungus (Histoplasma capsulatum) and is marked by benign involvement of lymph nodes of the trachea and bronchi or by severe progressive generalized involvement of the lymph nodes and tissues (as of the liver or spleen) rich in macrophages

Example Sentences

Recent Examples on the Web Typically, different fungal infections are associated with specific regions: Valley fever is most common in the Southwest, for example, whereas histoplasmosis is mostly identified in central and eastern states. Angela Yang, NBC News, 21 Nov. 2022 The standard antifungal treatment for histoplasmosis, a drug called itraconazole, proved tricky to prescribe in Jerry’s case because his liver disease altered the drug’s metabolism. Claire Panosian Dunavan, Discover Magazine, 24 Sep. 2010 The researchers found that 94% of U.S. states had at least one county with a significant number of histoplasmosis cases, and 69% had at least one county with a significant number of Valley fever cases. Angela Yang, NBC News, 21 Nov. 2022 Both diseases affect domestic birds, and histoplasmosis can be transferred to humans. Sheryl Devore, chicagotribune.com, 14 Apr. 2022 May 1997 - Is hospitalized for a fungal infection called histoplasmosis. Cnn Editorial Research, CNN, 6 May 2021 Remicade was first approved in 1998, and by 2001 there already were enough reports of invasive histoplasmosis cases that the FDA issued a black box warning for it and other drugs in its class. John Fauber, Milwaukee Journal Sentinel, 30 Nov. 2020 Tschannen died in an Illinois hospital that year of a fungal infection known as histoplasmosis, a condition that for most people causes only mild symptoms. John Fauber, Milwaukee Journal Sentinel, 30 Nov. 2020 Coming into contact with their feces can also put people at risk of infectious diseases, including histoplasmosis and Salmonella, reports Justin Rohrlich for Quartz. Katherine J. Wu, Smithsonian Magazine, 13 Jan. 2020 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'histoplasmosis.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

Etymology

New Latin, from Histoplasma, genus of fungi

First Known Use

1907, in the meaning defined above

Time Traveler
The first known use of histoplasmosis was in 1907

Dictionary Entries Near histoplasmosis

Cite this Entry

“Histoplasmosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/histoplasmosis. Accessed 2 Feb. 2023.

Medical Definition

histoplasmosis

noun
his·​to·​plas·​mo·​sis -ˌplaz-ˈmō-səs How to pronounce histoplasmosis (audio)
plural histoplasmoses -ˌsēz How to pronounce histoplasmosis (audio)
: a respiratory disease with symptoms like those of influenza that is endemic in the Mississippi and Ohio river valleys of the United States, is caused by infection with a fungus of the genus Histoplasma (H. capsulatum), and is marked by benign involvement of lymph nodes of the trachea and bronchi usually without symptoms or by severe progressive generalized involvement of the lymph nodes and macrophage-rich tissues (as of the liver and spleen) with fever, anemia, leukopenia and often with local lesions (as of the skin, mouth, or throat)

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