am·​y·​loid·​osis | \ ˌa-mə-ˌlȯi-ˈdō-səs How to pronounce amyloidosis (audio) \

Definition of amyloidosis

: a disorder characterized by the deposition of amyloid in bodily organs and tissues

Examples of amyloidosis in a Sentence

Recent Examples on the Web

In 2016, the company scrapped development of another RNAi drug for amyloidosis after a study showed a higher death rate among patients taking the drug, compared with a placebo. Peter Loftus, WSJ, "New Kind of Drug, Silencing Genes, Gets FDA Approval," 10 Aug. 2018 Ex-player, GM Millen ailing Former NFL player and general manager Matt Millen, 60, said he was being treated for amyloidosis, a rare disease that has left his heart functioning at just 30 percent., "UMass extends football coach Mark Whipple’s contract through 2020," 30 Apr. 2018 Casey, then 61, suffering from amyloidosis, a genetic disease, had a 13-hour heart-liver transplant at the University of Pittsburgh Medical Center. John Baer,, "Remembering the historic day Pa.'s Casey, Specter had critical surgeries | John Baer," 12 June 2018 The cause was complications related to amyloidosis, said his son-in-law, Stefan Merrill Block. Neil Genzlinger, New York Times, "Peter Mayer, Publisher of the Incendiary ‘Satanic Verses,’ Dies at 82," 11 May 2018 In a Phase 2 study, one year of treatment with NEOD001 failed to improve a biomarker of heart failure in previously treated patients with AL amyloidosis compared to a placebo, Prothena said. Adam Feuerstein, STAT, "Prothena scraps lead drug following mid-stage study failure," 23 Apr. 2018 Alnylam stuck with it, however, and expects to win government approval this year for the first gene-silencing drug, patisiran, to treat a rare degenerative disorder called hereditary ATTR amyloidosis. Jonathan Saltzman,, "Trade secrets battle between Alnylam, Dicerna is just one of many," 17 Apr. 2018 Millen, whose time running the Lions ushered in the lowest points of the franchise's history, was diagnosed with amyloidosis, an incurable disease that is being treated with chemotherapy. Kirkland Crawford, Detroit Free Press, "Matt Millen rips self for Detroit Lions era: 'I was not ready at all'," 14 May 2018 The experimental drug, called inotersen, lengthened its maximum demonstrated benefit from 15 months to 27 months in patients with hereditary ATTR amyloidosis. Bradley J. Fikes,, "Ionis reports continued success testing drug for fatal disease," 26 Mar. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'amyloidosis.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of amyloidosis

1886, in the meaning defined above

History and Etymology for amyloidosis

New Latin

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The first known use of amyloidosis was in 1886

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More Definitions for amyloidosis


am·​y·​loid·​o·​sis | \ ˌam-ə-ˌlȯi-ˈdō-səs How to pronounce amyloidosis (audio) \
plural amyloidoses\ -​ˌsēz How to pronounce amyloidoses (audio) \

Medical Definition of amyloidosis

: a disorder characterized by the deposition of amyloid in organs or tissues of the animal body — see paramyloidosis

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of or relating to a parable or parabola

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