hemophilia A

noun

Definition of hemophilia A

: the common form of hemophilia that is caused by a deficiency of factor VIII — compare hemophilia b

Examples of hemophilia A in a Sentence

Recent Examples on the Web About 1 in 10,000 people have hemophilia A, and about half of them have a severe case. CBS News, "FDA rejects Roctavian, BioMarin hemophilia drug," 19 Aug. 2020 In deciding not to approve Roctavian, a BioMarin Pharmaceutical gene therapy for hemophilia A, the FDA demanded two additional years of data to strengthen the case that its benefits are durable. Adam Feuerstein, STAT, "Stunning FDA rejection signals potential new hurdles for gene therapies," 20 Aug. 2020 Treating hemophilia A typically costs about $300,000 a year, according to the health care and biotech news site. CBS News, "FDA rejects Roctavian, BioMarin hemophilia drug," 19 Aug. 2020 Stimate nasal spray is used in treating certain patients with hemophilia A or those with mild to moderate classic von Willebrand's disease, a blood-clotting disorder. Kate Gibson, CBS News, "Certain nasal sprays recalled due to risks including seizure and death," 6 Aug. 2020 In 2017, the FDA approved Roche Holding AG ’s hemophilia A treatment, Hemlibra, which isn’t a gene therapy. Jared S. Hopkins, WSJ, "BioMarin Explores Pricing Experimental Gene Therapy at $2 Million to $3 Million," 16 Jan. 2020 But the new warning comes from larger, older animals: adult dogs with hemophilia A, in which a clotting protein called factor VIII is missing. Jocelyn Kaiser, Science | AAAS, "Virus used in gene therapies may pose cancer risk, dog study hints," 6 Jan. 2020 Regulators needed to be persuaded that Roche wasn’t just buying Spark and its hemophilia A treatment, currently in clinical studies, to thwart a potential competitor for Roche’s existing hemophilia drug. BostonGlobe.com, "Chief executive Sumit Singh," 26 Dec. 2019 Pfizer is in late testing of a gene therapy for hemophilia A and will launch three biosimilars, or near-copies of biologic drugs produced by living cells, from December through February. Washington Post, "Pfizer narrows its focus and profit soars in 3Q," 29 Oct. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'hemophilia A.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of hemophilia A

1954, in the meaning defined above

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The first known use of hemophilia A was in 1954

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Cite this Entry

“Hemophilia A.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hemophilia%20A. Accessed 5 Dec. 2020.

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More Definitions for hemophilia A

hemophilia A

noun

Medical Definition of hemophilia A

: the common form of hemophilia caused by a deficiency of factor VIII in the blood Some boys with hemophilia A are endangered by any bump or scrape, while others have such mild forms that the disorder goes undetected until they lose their first tooth.Science News, 10 Aug. 1991

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