hemophilia

noun
he·​mo·​phil·​ia | \ ˌhē-mə-ˈfi-lē-ə How to pronounce hemophilia (audio) \

Definition of hemophilia

: a hereditary, sex-linked blood defect occurring almost exclusively in males that is marked by delayed clotting of the blood with prolonged or excessive internal or external bleeding after injury or surgery and in severe cases spontaneous bleeding into joints and muscles and that is caused by a deficiency of clotting factors

Note: Hemophilia is inherited as an X-linked recessive trait in which the mother must pass on a copy of the defective gene to a male child, and more rarely, both parents must pass on copies of the defective gene to a female child.

— see hemophilia a, hemophilia b

Did you know?

The dreaded disease known as hemophilia is the result of an inherited gene, and almost always strikes boys rather than girls (though mothers may pass the gene to their sons). Since the blood lacks an ingredient that causes it to clot or coagulate when a blood vessel breaks, even a minor wound can cause a hemophiliac to bleed to death if not treated. Bleeding can be particularly dangerous when it's entirely internal, with no visible wound, since the person may not be aware it's happening. Queen Victoria transmitted the hemophilia gene to royal families all across Europe; the hemophilia of a young Russian prince played a part in the downfall of the Russian czars. Today, hemophiliacs take drugs that stop the bleeding by speeding coagulation, and hemophiliac life expectancies in developed countries are almost as long as the average.

Examples of hemophilia in a Sentence

Recent Examples on the Web That level is classified as a very mild hemophilia and doesn't require treatment. John Timmer, Ars Technica, 9 Dec. 2020 The hemophilia trial was typical of most early efforts at gene therapy. John Timmer, Ars Technica, 9 Dec. 2020 Drugs derived from plasma are used for treating ailments such as hemophilia and are showing promise in slowing the progression of Alzheimer’s. Emma Vickers, Bloomberg.com, 13 May 2020 It is designed for hemophilia patients to make the protein missing for blood-clotting. Jared S. Hopkins, WSJ, 16 Jan. 2020 Plasma is transformed into a wide variety of therapies that benefit thousands of people every day suffering from conditions such as hemophilia and immune deficiencies. Dallas News, 5 Feb. 2020 Last year, two of the most significant growth drivers were Ocrevus, for multiple sclerosis, and Hemlibra, for hemophilia. Denise Roland, WSJ, 30 Jan. 2020 The company also wrote down the value of hemophilia treatment Eloctate by €1.2 billion. Denise Roland, WSJ, 6 Feb. 2020 The Spark holdup confused the market because there are multiple other drugmakers developing hemophilia gene therapies. Washington Post, 17 Dec. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'hemophilia.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of hemophilia

1872, in the meaning defined above

History and Etymology for hemophilia

New Latin

Learn More About hemophilia

Time Traveler for hemophilia

Time Traveler

The first known use of hemophilia was in 1872

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Dictionary Entries Near hemophilia

hemophagocyte

hemophilia

hemophilia A

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Statistics for hemophilia

Cite this Entry

“Hemophilia.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hemophilia. Accessed 8 Dec. 2021.

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More Definitions for hemophilia

hemophilia

noun

English Language Learners Definition of hemophilia

: a serious disease that causes a person who has been cut or injured to keep bleeding for a very long time

hemophilia

noun
he·​mo·​phil·​ia
variants: or chiefly British haemophilia \ ˌhē-​mə-​ˈfil-​ē-​ə How to pronounce hemophilia (audio) \

Medical Definition of hemophilia

: a tendency to uncontrollable bleeding especially : a hereditary, sex-linked blood disorder occurring almost exclusively in males that is marked by delayed clotting of the blood with prolonged or excessive internal or external bleeding after injury or surgery and in severe cases spontaneous bleeding into joints and muscles and that is caused by a deficiency of clotting factors

Note: Hemophilia is inherited as an X-linked recessive trait in which the mother must pass on a copy of the defective gene to a male child, and more rarely, both parents must pass on copies of the defective gene to a female child.

— see hemophilia a, hemophilia b — compare von willebrand disease

More from Merriam-Webster on hemophilia

Nglish: Translation of hemophilia for Spanish Speakers

Britannica.com: Encyclopedia article about hemophilia

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