hand, foot and mouth disease

noun

: a usually mild contagious disease especially of young children that is caused by an enterovirus (Enterovirus alphacoxsackie and especially serotypes coxsackievirus A16 and enterovirus A71) and is characterized by vesicular lesions chiefly in the mouth and on the hands and feet compare foot-and-mouth disease

Examples of hand, foot and mouth disease in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Most respiratory viruses, including Covid-19, flu and RSV, act through the indirect pathway, Roberts said, while enterovirus strains – related to the viruses that cause hand, foot and mouth disease – can directly infect the heart muscle. Asuka Koda, CNN Money, 29 Oct. 2025 One of the first places where hand, foot and mouth disease reportedly spread was at Sherwood Elementary, located in Memphis Tenn., which alerted parents to the outbreak in a letter issued on Aug. 27, according to local outlet ABC24. Kimberlee Speakman, PEOPLE, 24 Oct. 2025 Experts are now warning that the declines in vaccine coverage in the United States has led to notable increases in several diseases, including measles, whooping cough and hand, foot and mouth disease. Sonam Sheth, MSNBC Newsweek, 6 Aug. 2025 The usual fall culprits include respiratory viruses like the common cold, influenza, croup, COVID-19, RSV, and hand, foot and mouth disease. Dallas News, 11 Oct. 2022 Other enteroviruses cause polio and hand, foot and mouth disease. Will Sullivan, Smithsonian Magazine, 15 Sep. 2022 Tomato flu could also be a new variant of hand, foot and mouth disease, which is common among children under age 5, the Lancet article said. Andrew Jeong, Washington Post, 25 Aug. 2022 Prior to Tommy John surgery, Syndergaard has dealt with various ailments in his big-league career, twice landing on the Disabled List (now called the Injured List) in 2018, for a strained ligament in his right index finger, and for contracting hand, foot and mouth disease. Christian Red, Forbes, 30 May 2021

Word History

First Known Use

1966, in the meaning defined above

Time Traveler
The first known use of hand, foot and mouth disease was in 1966

Browse Nearby Words

See all Nearby Words

Cite this Entry

“Hand, foot and mouth disease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hand%2C%20foot%20and%20mouth%20disease. Accessed 11 Nov. 2025.

Medical Definition

hand, foot and mouth disease

noun
: a usually mild contagious viral disease especially of young children that is characterized by fever, malaise, sore throat, and typically painful fluid-filled blisters in the mouth, on the hands and feet, and sometimes in the diaper-covered area and is caused by an enterovirus (Enterovirus alphacoxsackie and especially serotypes coxsackievirus A16 and enterovirus A71) compare foot-and-mouth disease
Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!