glu·​ta·​mate | \ ˈglü-tə-ˌmāt How to pronounce glutamate (audio) \

Definition of glutamate

: a salt or ester of glutamic acid specifically : a salt or ester of levorotatory glutamic acid that functions as an excitatory neurotransmitter — compare monosodium glutamate

Examples of glutamate in a Sentence

Recent Examples on the Web And what is being sent through those networks are [chemicals] like glutamate, which is an amino acid that also serves as a neurotransmitter in our brain. Richard Schiffman, Scientific American, 4 May 2021 One theory is that NAC helps limit the release of a chemical known as glutamate in the part of the brain responsible for reward-seeking behaviors like drug use, nail biting or skin picking. Cezary Podkul, WSJ, 28 Dec. 2020 In one study, researchers attached the gene-editing technology CRISPR/CAS 9 to a nanoparticle to disrupt the gene for mGluR5 receptors for the neurotransmitter glutamate, implicated in fragile X syndrome and other forms of autism. Lydia Denworth, Science | AAAS, 14 Oct. 2020 Tau, for instance, accumulates in neurons that use the neurotransmitter glutamate and work to excite signals. Kenneth S. Kosik, Scientific American, 20 Apr. 2020 All of these ingredients are rich in glutamates, the chemical compounds largely responsible for the mouthwatering savory flavor known as umami. J. Kenji López-alt, New York Times, 3 Mar. 2020 Pizza toppings are also packed with a compound called glutamate, which can be found in the tomatoes, cheese, pepperoni and sausage. Jeffrey Miller, Washington Post, 4 Nov. 2019 In addition to glutamate, two other molecules, inosinate and guanylate, emit umami. Elizabeth G. Dunn, WSJ, 30 Jan. 2020 The treatment, Caplyta, is the drug developer’s lead candidate that has been shown to regulate three neurotransmitter systems — serotonin, dopamine and glutamate — linked to severe mental illnesses. Washington Post, 23 Dec. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'glutamate.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of glutamate

1876, in the meaning defined above

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Time Traveler for glutamate

Time Traveler

The first known use of glutamate was in 1876

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Statistics for glutamate

Last Updated

16 May 2021

Cite this Entry

“Glutamate.” Dictionary, Merriam-Webster, Accessed 15 Jun. 2021.

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More Definitions for glutamate


glu·​ta·​mate | \ ˈglüt-ə-ˌmāt How to pronounce glutamate (audio) \

Medical Definition of glutamate

: a salt or ester of glutamic acid specifically : a salt or ester of levorotatory glutamic acid that functions as an excitatory neurotransmitter — see monosodium glutamate

More from Merriam-Webster on glutamate Encyclopedia article about glutamate


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