glutamate

noun

glu·​ta·​mate ˈglü-tə-ˌmāt How to pronounce glutamate (audio)
: a salt or ester of glutamic acid
specifically : a salt or ester of levorotatory glutamic acid that functions as an excitatory neurotransmitter compare monosodium glutamate

Examples of glutamate in a Sentence

Recent Examples on the Web
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In 1908, a Japanese professor named Kikunae Ikeda discovered that glutamate was the source of the savory flavor of seaweed broth and filed a patent to start commercially producing it. Caroline Tien, SELF, 23 Feb. 2026 Osmond and her sisters have variations on a gene that affects receptors for glutamate, an excitatory neurotransmitter with many functions throughout the brain. Shayla Love, New Yorker, 18 Feb. 2026 One day in 1989, Smith’s graduate student Steve Finkbeiner (now a neurologist at the nonprofit Gladstone Institutes in San Francisco) was using the microscope to explore the potentially toxic effects of the neurotransmitter glutamate, the molecule most neurons in the brain use to communicate. Ingrid Wickelgren, Quanta Magazine, 30 Jan. 2026 The torpor phase enables the squirrel to suppress activity within ion channels, reduce the release of glutamate and stabilize its cell membranes. Scott Travers, Forbes.com, 24 Jan. 2026 See All Example Sentences for glutamate

Word History

First Known Use

1876, in the meaning defined above

Time Traveler
The first known use of glutamate was in 1876

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Cite this Entry

“Glutamate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/glutamate. Accessed 25 Feb. 2026.

Medical Definition

glutamate

noun
glu·​ta·​mate ˈglüt-ə-ˌmāt How to pronounce glutamate (audio)
: a salt or ester of glutamic acid
specifically : a salt or ester of levorotatory glutamic acid that functions as an excitatory neurotransmitter see monosodium glutamate

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