gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌga-strō-in-ˈte-stə-nᵊl 

-ˈtes(t)-nəl

: of, relating to, affecting, or including both stomach and intestine

Examples of gastrointestinal in a Sentence

Recent Examples on the Web

The image left in my head, though, is of the toilet bowl being frantically flushed by Charlotte’s art-dealer boss, a man whose private jet can’t spare him from the gastrointestinal Thanksgiving issues of a lactose-intolerant Gen Zer. —Sophie Gilbert, The Atlantic, 15 Aug. 2025

Previous research has shown that in the five to 10 years leading up to an MS diagnosis, people typically seek medical attention more frequently for headaches, fatigue, sleep disorders, pain, gastrointestinal issues and psychiatric concerns, the researchers wrote. —Deirdre Bardolf, FOXNews.com, 15 Aug. 2025

The most common side effects were mild to moderate gastrointestinal issues, with about one-third of patients on the highest orforglipron dose experiencing nausea and about one-quarter experiencing constipation or diarrhea. —Emily Kay Votruba, EverydayHealth.com, 11 Aug. 2025

To avoid bloating and other gastrointestinal symptoms, add fiber to your diet slowly and drink plenty of water. —Dr. Roshini Raj, Health, 7 Aug. 2025

Word History

First Known Use

1831, in the meaning defined above

Phrases Containing gastrointestinal

• gastrointestinal tract

Rhymes for gastrointestinal

• intestinal

Kids Definition

gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌgas-trō-in-ˈtes-tən-ᵊl 

: of, relating to, or including both stomach and intestine

Medical Definition

gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌgas-trō-in-ˈtes-tən-ᵊl, -ˈtes(t)-nəl 

: of, relating to, or affecting both stomach and intestine

gastrointestinal distress