gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌga-strō-in-ˈte-stə-nᵊl 

-ˈtes(t)-nəl

: of, relating to, affecting, or including both stomach and intestine

Examples of gastrointestinal in a Sentence

Recent Examples on the Web

Antibiotics can also lead to gastrointestinal side effects that could hinder koalas' ability to digest eucalyptus leaves, which are the animals' main food source. —Chandelis Duster, NPR, 14 Sep. 2025

In August, Bhagwandin and his team performed their first robotic Whipple surgery—a complex procedure used to treat used to treat pancreatic cancer, cysts, tumors and pancreatitis along with other gastrointestinal conditions. —Alexis Kayser, MSNBC Newsweek, 11 Sep. 2025

Ketamine therapy’s most common short-term side effects are dizziness and nausea, but in extreme cases, long-term, heavy use of ketamine is associated with memory problems, gastrointestinal issues, and urinary tract infections, according to the National Institute on Drug Abuse. —Rachel Hale, USA Today, 10 Sep. 2025

The most prevalent is gastrointestinal issues, such as nausea and vomiting. —Melissa Rudy, FOXNews.com, 10 Sep. 2025

Word History

First Known Use

1831, in the meaning defined above

Phrases Containing gastrointestinal

• gastrointestinal tract

Rhymes for gastrointestinal

• intestinal

Kids Definition

gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌgas-trō-in-ˈtes-tən-ᵊl 

: of, relating to, or including both stomach and intestine

Medical Definition

gastrointestinal

adjective

gas·​tro·​in·​tes·​ti·​nal ˌgas-trō-in-ˈtes-tən-ᵊl, -ˈtes(t)-nəl 

: of, relating to, or affecting both stomach and intestine

gastrointestinal distress