: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
epinephrine is a fight-or-flight hormone
a fight-or-flight reaction

Examples of fight-or-flight in a Sentence

Recent Examples on the Web
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Stepping into a room that hot triggers an immediate stress reaction, activating the sympathetic arm of the nervous system, the fight-or-flight response. Will Stone, NPR, 6 Mar. 2026 Now, adrenaline is a different hormone that regulates the fight-or-flight response. Caitlin Pagán, Verywell Health, 3 Mar. 2026 This allows an athlete like Shiffrin to override the fight-or-flight response. Sally Jenkins, The Atlantic, 21 Feb. 2026 The aim, it is explained, is to stimulate his parasympathetic nervous system — to remove the fight-or-flight response activated by racing, to help the brain switch off. Jacob Whitehead, New York Times, 21 Feb. 2026 See All Example Sentences for fight-or-flight

Word History

First Known Use

1973, in the meaning defined above

Time Traveler
The first known use of fight-or-flight was in 1973

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Cite this Entry

“Fight-or-flight.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fight-or-flight. Accessed 9 Mar. 2026.

Medical Definition

fight-or-flight

adjective
ˌfī-tər-ˈflīt
: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
the fight-or-flight response
Last Updated: - Updated example sentences
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