: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
epinephrine is a fight-or-flight hormone
a fight-or-flight reaction

Examples of fight-or-flight in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Oxytocin shifts your body out of fight-or-flight mode. Laura Kiniry, Popular Science, 17 June 2026 That asymmetry creates enormous opportunities for startups facing fight-or-flight moments. Matt Rogers, Fortune, 30 May 2026 As the gut is considered a second brain, the process involves listening in with a stethoscope while manual, hands-on therapy helps the body shift more easily between fight-or-flight and not get stuck in one. Lydia Bell, Condé Nast Traveler, 23 June 2026 Mayo Clinic Press notes that anxiety triggers labored breathing, muscle tightening and activation of the sympathetic nervous system, the body’s fight-or-flight wiring. Allison Palmer, Miami Herald, 6 May 2026 See All Example Sentences for fight-or-flight

Word History

First Known Use

1973, in the meaning defined above

Time Traveler
The first known use of fight-or-flight was in 1973

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Cite this Entry

“Fight-or-flight.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fight-or-flight. Accessed 8 Jul. 2026.

Medical Definition

fight-or-flight

adjective
ˌfī-tər-ˈflīt
: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
the fight-or-flight response
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