ergotamine

noun
er·got·a·mine | \(ˌ)ər-ˈgä-tə-ˌmēn \

Definition of ergotamine 

: an alkaloid C33H35N5O5 derived from ergot that is used chiefly in the form of its tartrate especially in treating migraine

Examples of ergotamine in a Sentence

Recent Examples on the Web

The first such drugs, called ergotamines, were powerful vasoconstrictors derived from the ergot fungus, which grows on rye and other grains and led to mass poisonings in the Middle Ages. Emily Underwood, Science | AAAS, "Will antibodies finally put an end to migraines?," 18 May 2018 That idea was reinforced in the late 1930s with the publication of a paper on the use of ergotamine tartrate, an alkaloid that was known to constrict blood vessels. David Noonan, Scientific American, "New Nerve Drugs May Finally Prevent Migraine Headaches," 1 Dec. 2015 Yet even refined, synthetic versions of ergotamine can dangerously narrow blood vessels, so doctors and patients welcomed the triptans, which selectively constrict the blood vessels of the brain. Emily Underwood, Science | AAAS, "Will antibodies finally put an end to migraines?," 18 May 2018 As treatments, though, ergotamine and serotonin have serious problems. R. Allan Purdy, Scientific American, "Can Anything Stop My Migraine?," 1 May 2017 The result, after a decade of work, was sumatriptan, which, like ergotamine, both eased pain and constricted blood vessels. R. Allan Purdy, Scientific American, "Can Anything Stop My Migraine?," 1 May 2017 While some people are helped by low cost, over-the-counter drugs such as ibuprofen, others need stronger prescription medications, such as sumatriptan and ergotamine, which constrict the blood vessels in the brain and can cause dizziness or nausea. NBC News, "New drug uses antibodies to stop chronic migraines, without side effects," 17 Apr. 2018 It is normally associated with certain medications, such as ergotamine or triptans, and illicit drugs, such as cocaine and amphetamines -- not peppers. Mark Lieber, CNN, "Brain effects of 'hottest pepper in the world' put man in hospital," 9 Apr. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'ergotamine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of ergotamine

1921, in the meaning defined above

History and Etymology for ergotamine

International Scientific Vocabulary

Keep scrolling for more

Learn More about ergotamine

Share ergotamine

Dictionary Entries near ergotamine

ergonovine

ergosterol

ergot

ergotamine

ergotised

ergotism

ergotize

Statistics for ergotamine

Last Updated

16 Oct 2018

Look-up Popularity

Time Traveler for ergotamine

The first known use of ergotamine was in 1921

See more words from the same year

Keep scrolling for more

More Definitions for ergotamine

ergotamine

noun
er·got·a·mine | \(ˌ)ər-ˈgät-ə-ˌmēn \

Medical Definition of ergotamine 

: an alkaloid that is derived from ergot and is used chiefly in the form of its tartrate (C33H35N5O5)2·C4H6O6 especially in treating migraine

More from Merriam-Webster on ergotamine

Britannica.com: Encyclopedia article about ergotamine

Comments on ergotamine

What made you want to look up ergotamine? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

exaggeratedly or childishly emotional

Get Word of the Day daily email!

Test Your Vocabulary

Words from Greek and Roman Mythology Quiz

  • the-triumph-of-venus-by-alessandro-magnasco
  • Boreal comes from the name of the ancient Greek god of which wind?
True or False

Test your knowledge - and maybe learn something along the way.

TAKE THE QUIZ
Word Winder's CrossWinder

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!