endocannabinoid

noun

en·​do·​can·​na·​bi·​noid ˌen-dō- kə-ˈna-bə-ˌnȯid How to pronounce endocannabinoid (audio)
-ˈka-nə-bə-ˌnȯid
plural endocannabinoids
: any of several chemical compounds (such as anandamide) that are naturally produced within the body and bind to the same brain receptors as compounds (such as THC) derived from cannabis : cannabinoid sense 2a
In other studies, endocannabinoid levels have been shown to increase after prolonged running and cycling, leading many scientists to conclude that endocannabinoids help to create runner's high.Gretchen Reynolds

Examples of endocannabinoid in a Sentence

Recent Examples on the Web The innumerable aspects of the still-mysterious human endocannabinoid system are mostly unknown, too. Nicholas Florko and Sarah Owermohle, STAT, 30 May 2024 Research is building to show how THC interacts with the body’s endocannabinoid system (ECS), a complex network of receptors and neurotransmitters that play a crucial role in regulating various physiological processes. Calvin Rasode, Rolling Stone, 24 Apr. 2024 These receptors form the endocannabinoid system, which acts as conductor for an orchestra of neurotransmitters, turning up or down the volume on sleep, temperature, pain, hunger, learning, and memory. Julia Michie Bruckner, Discover Magazine, 5 Apr. 2024 Across vertebrate species, these molecules interact with the endocannabinoid system, a network of nerve receptors, molecules and enzymes that keeps the body’s other organ systems stable. Rachel Nuwer, New York Times, 6 Feb. 2024 The former works to depress the central nervous system, temporarily putting your brain in chill mode while the liver metabolizes it; the latter conversely activates the endocannabinoid receptors in your brain. Ali Finney, SELF, 26 Feb. 2024 Meanwhile, individuals with PTSD are understood to have lower levels of the neurotransmitter anandamide, an endocannabinoid that binds to CB1 receptors in the body and interacts with the cannabinoid CBD. Sarah Sinclair, Forbes, 15 Feb. 2024 Education for fellow veterinarians is also warranted, Dr. Andre said — not only about the medical use of cannabis, but also about the endocannabinoid system itself, which only recently entered the curriculum at veterinary schools after being discovered in 1988. Rachel Nuwer, New York Times, 6 Feb. 2024 This natural compound derived from the cannabis plant interacts with the endocannabinoid system, which plays a crucial role in regulating pain perception and immune response. Amber Smith, Discover Magazine, 5 Nov. 2023

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'endocannabinoid.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1997, in the meaning defined above

Time Traveler
The first known use of endocannabinoid was in 1997

Dictionary Entries Near endocannabinoid

Cite this Entry

“Endocannabinoid.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/endocannabinoid. Accessed 15 Jul. 2024.

Medical Definition

endocannabinoid

noun
en·​do·​can·​na·​bi·​noid
ˌen-dō-ˈkan-ə-bə-ˌnȯid,
-kə-ˈnab-ə- How to pronounce endocannabinoid (audio)
: any of several chemical compounds (as anandamide) that are naturally produced within the body and bind to the same brain receptors as compounds (as THC) derived from cannabis : cannabinoid sense 2a
In other studies, endocannabinoid levels have been shown to increase after prolonged running and cycling, leading many scientists to conclude that endocannabinoids help to create runner's high.Gretchen Reynolds
Scientists have come to recognize that endocannabinoids interact with a specific neurological network—much the way that endorphins, serotonin, and dopamine do.Hampton Sides
Last Updated: - Updated example sentences
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