can·na·bi·noid | \kə-ˈna-bə-ˌnȯid \

Definition of cannabinoid 

1 : any of various naturally-occurring, biologically active, chemical constituents (such as cannabidiol or cannabinol) of hemp or cannabis including some (such as THC) that possess psychoactive properties The presence of cannabinoids in urine indicates marijuana use, and a great deal of weight is often placed on positive findings.— Arthur J. McBay, et al The study concluded that cannabinoids—marijuana's active components—can be useful in treating pain, nausea and appetite loss caused by advanced cancer and AIDS.— Claudia Kalb

2 : a substance that is structurally or functionally similar to cannabinoids derived from hemp or cannabis:

a : any of several substances (as anandamide) naturally produced within the body : endocannabinoid Move over, endorphins. Postexercise euphoria may actually be the result of naturally occurring cannabinoids—the same family of chemicals that gives marijuana smokers their high, a new study suggests.Prevention Daniele Piomelli and his colleagues report isolating from cocoa powder and three different brands of chocolate a substance called anandamide, a cannabinoid that occurs naturally in the brain.Science News

b : a substance that is synthetically produced to mimic the effects of natural cannabinoids Toxicologists know only that synthetic cannabinoids bind to certain receptors in the brain and they understand nothing about drug's long-term health effects.— Steve Featherstone These products contain synthetic cannabinoids, which produce some of the euphoria associated with natural marijuana, but they can also be accompanied by a wide range of negative health effects not associated with cannabis.— James Maynard

Examples of cannabinoid in a Sentence

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Sometimes the substance is laced with other pharmaceuticals or synthetic cannabinoids -- chemicals that can mimic the effects of tetrahydrocannabinol, or THC, the active ingredient in marijuana. Samantha Ketterer, Houston Chronicle, "North Houston smoke shop temporarily closed after police find synthetic cannabinoids," 22 June 2018 The synthetic cannabinoids were found to contain rat poison and most of the hospitalizations were related to unexplained bleeding, such as coughing up blood, blood in the urine, bloody nose and bleeding gums. Marlena Baldacci And Susannah Cullinane, CNN, "NYPD warns of toxic batch of fake weed K2 after overdoses," 22 May 2018 Basically, there is a ton of research into marijuana and its many, many components (called cannabinoids) as potential medicines. Andrew Joseph, STAT, "Archived chat: STAT on Marijuana-based medicine and drug development," 28 June 2018 Cannabis contains numerous compounds called cannabinoids. Christy Brissette,, "Milk, bread, hemp oil? On 4/20, a dietitian's guide to the cannabis items in your grocery store," 20 Apr. 2018 After overdoses from drugs like K2 surged in New York in 2015, the authorities carried out months of raids and the city passed legislation banning synthetic cannabinoids. New York Times, "K2 Eyed as Culprit After 14 People Overdose in Brooklyn," 20 May 2018 People are surprised to know that animals have an endo-cannabinoid system, too, and that hemp and cannabis work the same way for them. Erin Sauder, Elgin Courier-News, "Down to Business: West Dundee center helps clients learn about hemp-based products, apply for medical cannabis," 11 July 2018 State law outlaws certain synthetic cannabinoids, but drug makers have repeatedly changed the ingredients slightly to get around the prohibition. Robert Mccoppin,, "More people sickened by synthetic marijuana believed to be tainted with rat poison," 25 June 2018 Their Sympa-tea and Positivi-tea also contain CBD, a non-psychotropic cannabinoid that counteracts THC and the sensation of being high. Steffi Victorioso, Los Angeles Magazine, "Local Women Are Hosting Fancy “High Teas” With the Help of a Cannabis Brand," 29 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cannabinoid.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of cannabinoid

1967, in the meaning defined at sense 1

History and Etymology for cannabinoid

Latin cannabis + -in entry 1 + -oid entry 1

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28 Sep 2018

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The first known use of cannabinoid was in 1967

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can·na·bi·noid | \ˈkan-ə-bə-ˌnȯid, kə-ˈnab-ə- \

Medical Definition of cannabinoid 

: any of various chemical constituents (as THC) of cannabis or marijuana

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