can·​na·​bi·​noid | \kə-ˈna-bə-ˌnȯid \

Definition of cannabinoid 

1 : any of various naturally-occurring, biologically active, chemical constituents (such as cannabidiol or cannabinol) of hemp or cannabis including some (such as THC) that possess psychoactive properties The presence of cannabinoids in urine indicates marijuana use, and a great deal of weight is often placed on positive findings.— Arthur J. McBay, et al The study concluded that cannabinoids—marijuana's active components—can be useful in treating pain, nausea and appetite loss caused by advanced cancer and AIDS.— Claudia Kalb

2 : a substance that is structurally or functionally similar to cannabinoids derived from hemp or cannabis:

a : any of several substances (as anandamide) naturally produced within the body : endocannabinoid Move over, endorphins. Postexercise euphoria may actually be the result of naturally occurring cannabinoids—the same family of chemicals that gives marijuana smokers their high, a new study suggests.Prevention Daniele Piomelli and his colleagues report isolating from cocoa powder and three different brands of chocolate a substance called anandamide, a cannabinoid that occurs naturally in the brain.Science News

b : a substance that is synthetically produced to mimic the effects of natural cannabinoids Toxicologists know only that synthetic cannabinoids bind to certain receptors in the brain and they understand nothing about drug's long-term health effects.— Steve Featherstone These products contain synthetic cannabinoids, which produce some of the euphoria associated with natural marijuana, but they can also be accompanied by a wide range of negative health effects not associated with cannabis.— James Maynard

Examples of cannabinoid in a Sentence

Recent Examples on the Web

Local media reported a synthetic cannabinoid as the substance in question. Paulina Dedaj, Fox News, "Pennsylvania state prisons locked down after 'unknown substance' sickens staff members," 30 Aug. 2018 Police said Monday that samples of the drug tested postive for AB Fubinaca, a synthethic cannabinoid that has sickened people across the country. Dave Collins, The Seattle Times, "Trump drug czar nominee visits Connecticut after overdoses," 20 Aug. 2018 For the uninitiated, CBD stands for cannabidiol, which is a cannabinoid found in the cannabis plant. Lindsey Unterberger, Glamour, "I Replaced My Entire Beauty Routine With Only CBD Products," 14 Aug. 2018 This is the second-most-prevalent cannabinoid in marijuana. Michael Zoorob, Washington Post, "How will you know if there’s E. coli in your marijuana? No one’s figured out how to test and regulate it yet.," 19 Mar. 2018 One of over 80 compounds called cannabinoids extracted from the cannabis sativa plant. Allure, "The Skin-Care Glossary: A Comprehensive Guide to Everything You Need to Know," 17 Aug. 2018 The effects of cannabinoids are concentration-specific. Cady Drell, Marie Claire, "How Hard Should We Lean into This Whole CBD Coffee Trend?," 16 Aug. 2018 Sometimes the substance is laced with other pharmaceuticals or synthetic cannabinoids -- chemicals that can mimic the effects of tetrahydrocannabinol, or THC, the active ingredient in marijuana. Samantha Ketterer, Houston Chronicle, "North Houston smoke shop temporarily closed after police find synthetic cannabinoids," 22 June 2018 The synthetic cannabinoids were found to contain rat poison and most of the hospitalizations were related to unexplained bleeding, such as coughing up blood, blood in the urine, bloody nose and bleeding gums. Marlena Baldacci And Susannah Cullinane, CNN, "NYPD warns of toxic batch of fake weed K2 after overdoses," 22 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cannabinoid.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of cannabinoid

1967, in the meaning defined at sense 1

History and Etymology for cannabinoid

Latin cannabis + -in entry 1 + -oid entry 1

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7 Dec 2018

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The first known use of cannabinoid was in 1967

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can·​na·​bi·​noid | \ˈkan-ə-bə-ˌnȯid, kə-ˈnab-ə- \

Medical Definition of cannabinoid 

: any of various chemical constituents (as THC) of cannabis or marijuana

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