Down syndrome

noun

variants or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, upward slanting eyes, a flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21

called also trisomy 21

Examples of Down syndrome in a Sentence

Recent Examples on the Web Erskine’s fourth child, Jimmy, was born with Down syndrome. Houston Mitchell, Los Angeles Times, 19 Apr. 2024 Gigi’s Playhouse is a 501c3 nonprofit created to support people diagnosed with Down syndrome and their families. Meghan Overdeep, Southern Living, 18 Apr. 2024 His support of the Special Olympics and related causes, inspired by his son Jimmy, who led a life beyond all expectations when he was born with Down syndrome, cemented his legacy. CBS News, 16 Apr. 2024 The incidence of Down syndrome rose in early Iron Age Spain. Nick Bowlin, Harper's Magazine, 30 Mar. 2024 According to the complaint, the family was sitting at a nearby table when George approached them and started mocking the couple's daughter, who was described as having Down syndrome and was wheelchair bound. Stepheny Price, Fox News, 5 Apr. 2024 That pregnancy took a dramatic turn, however, when the couple was told that their baby had a 100 percent chance of being born with Down syndrome. Virginia Chamlee, Peoplemag, 4 Apr. 2024 While most workers have intellectual disabilities that can include cerebral palsy or Down syndrome, federal regulations list blindness, alcoholism and drug addiction as qualifying disabilities for lower pay. Tribune News Service, The Mercury News, 4 Apr. 2024 But the afternoon-long event centers around helping people with physical, developmental and cognitive disabilities such as cerebral palsy, Down syndrome and autism view and participate in the eclipse. USA TODAY, 30 Mar. 2024

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'Down syndrome.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

J. L. H. Down †1896 English physician

First Known Use

1961, in the meaning defined above

Time Traveler
The first known use of Down syndrome was in 1961

Dictionary Entries Near Down syndrome

Cite this Entry

“Down syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Down%20syndrome. Accessed 28 Apr. 2024.

Kids Definition

Down syndrome

noun
ˈdau̇n-
variants or Down's syndrome
ˈdau̇n(z)-
: a genetic condition characterized especially by developmental delays, by distinctive physical traits (as short stature and upward slanting eyes), and by the presence of three chromosomes numbered 21 in human beings
Etymology

named for J.L.H. Down, 1828–1896, English doctor

Medical Definition

Down syndrome

noun
variants or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, relatively small head, upward slanting eyes usually with epicanthal folds, flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21

called also Down, Down's, trisomy 21

More from Merriam-Webster on Down syndrome

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