Down syndrome
noun
variants
or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, upward slanting eyes, a flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21
called also trisomy 21
Examples of Down syndrome in a Sentence
Recent Examples on the Web
Hundreds have commented with overwhelming support and many others shared their own experiences with Down syndrome.
—
Daniella Gray, MSNBC Newsweek, 21 July 2025
People with intellectual disabilities, such as those with Down syndrome or fetal alcohol spectrum disorder, have historically had shorter life expectancies than the general population, but data from a Population Reference Bureau study found that the gap is shrinking.
—Karen Fonseth, Forbes.com, 18 July 2025
Courtney and Spencer Morey sued the Aledo Independent School District last year, arguing that the district was violating the Americans with Disabilities Act by denying special education services to their 4-year-old daughter, Annie, who has Down syndrome.
—Silas Allen, Fort Worth Star-Telegram, 17 July 2025
But Shannon French, a Meridian single mother who provided care for her children with Down syndrome and autism, argued that ending the program would just push families to rely more on other social programs.
—Sarah Cutler
updated July 16, Idaho Statesman, 16 July 2025
See All Example Sentences for Down syndrome
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Daniella Gray, MSNBC Newsweek, 21 July 2025
People with intellectual disabilities, such as those with Down syndrome or fetal alcohol spectrum disorder, have historically had shorter life expectancies than the general population, but data from a Population Reference Bureau study found that the gap is shrinking.
—Karen Fonseth, Forbes.com, 18 July 2025
Courtney and Spencer Morey sued the Aledo Independent School District last year, arguing that the district was violating the Americans with Disabilities Act by denying special education services to their 4-year-old daughter, Annie, who has Down syndrome.
—Silas Allen, Fort Worth Star-Telegram, 17 July 2025
But Shannon French, a Meridian single mother who provided care for her children with Down syndrome and autism, argued that ending the program would just push families to rely more on other social programs.
—Sarah Cutler
updated July 16, Idaho Statesman, 16 July 2025
See All Example Sentences for Down syndrome
Cite this Entry
“Down syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Down%20syndrome. Accessed 1 Aug. 2025.
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