diphenhydramine

noun
di·​phen·​hy·​dra·​mine | \ ˌdī-ˌfen-ˈhī-drə-ˌmēn How to pronounce diphenhydramine (audio) \

Definition of diphenhydramine

: an antihistamine C17H21NO used especially in the form of its hydrochloride

Examples of diphenhydramine in a Sentence

Recent Examples on the Web This group includes many over-the-counter sleep medicines, such as those containing diphenhydramine. Dr. Keith Roach, oregonlive, "Dear Doctor: Will this surgery help the pinched nerve in my neck?," 29 Mar. 2021 Benadryl contains diphenhydramine, an antihistamine that temporarily relieves symptoms caused by hay fever, upper respiratory allergies or the common cold, such as a runny nose and sneezing. Kate Gibson, CBS News, "TikTok "Benadryl Challenge" prompts FDA warning on overdoses," 25 Sep. 2020 Many of these adverse effects are due to the fact that diphenhydramine is not just an antihistamine, Dr. Stolbach explains. Sarah Jacoby, SELF, "Seriously, Do Not Take the TikTok ‘Benadryl Challenge’," 4 Sep. 2020 During the investigation, police found empty containers of diphenhydramine at the house where Banas was living in 2014. Bruce Vielmetti, Milwaukee Journal Sentinel, "Former Cedarburg restaurant operator guilty in drink spiking case," 26 Feb. 2020 Other drugs linked to overdose deaths were benzodiazepines; diphenhydramine, an antihistamine; and gabapentin, an anticonvulsant. Nadia Kounang, CNN, "Fentanyl is the deadliest drug in the US, but in some places, meth kills more," 25 Oct. 2019 Doxylamine and diphenhydramine are antihistamines that can be used as sleeping aids. Bruce Vielmetti, Milwaukee Journal Sentinel, "Former Cedarburg restaurant operator guilty in drink spiking case," 26 Feb. 2020 The cameras captured video of Brian Kozlowski pouring diphenhydramine, an antihistamine mainly used to treat allergies or for insomnia, into her coffee on multiple occasions, according to authorities. Janelle Griffith, NBC News, "Michigan man sentenced to 60 weekend days in jail for poisoning wife's coffee," 2 Aug. 2019 Those include sedatives such as aplrazolam (sold as Xanax), clonazepam (sold as Klonopin) and diazepam (sold as Valium), as well as the antihistamine diphenhydramine (sold as Benadryl), and a number of other powerful narcotics and opioids. Erika Edwards, NBC News, "The drugs behind deadly overdoses vary across the United States.," 25 Oct. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'diphenhydramine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of diphenhydramine

1948, in the meaning defined above

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The first known use of diphenhydramine was in 1948

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Last Updated

9 Apr 2021

Cite this Entry

“Diphenhydramine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/diphenhydramine. Accessed 16 Apr. 2021.

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More Definitions for diphenhydramine

diphenhydramine

noun
di·​phen·​hy·​dra·​mine | \ ˌdī-ˌfen-ˈhī-drə-ˌmēn How to pronounce diphenhydramine (audio) \

Medical Definition of diphenhydramine

: an antihistamine used especially in the form of its hydrochloride C17H21NO·HCl to treat allergy symptoms and motion sickness and to induce sleep — see benadryl

More from Merriam-Webster on diphenhydramine

Britannica.com: Encyclopedia article about diphenhydramine

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