dif·​fi·​cile | \ˌdē-fi-ˈsēl \

Definition of difficile 

Examples of difficile in a Sentence

Recent Examples on the Web

Later this year, Vedanta plans to start mid-stage clinical trials of a medicine for Clostridium difficile infection, a potentially deadly disorder that often afflicts elderly people taking antibiotics in health care facilities. Jonathan Saltzman, BostonGlobe.com, "Startup aims to make allies of human gut’s microbes," 19 June 2018 That is what has been happening for decades with all sorts of infections, from methicillin-resistant Staphylococcus aureus (MRSA) to killer Clostridium difficile infections. NBC News, ""Nightmare bacteria" are trying to spread in the U.S., CDC says," 3 Apr. 2018 That’s why fecal transplants are being used to treat patients with Clostridium difficile infections, which can cause fatal chronic diarrhea. NBC News, "Could these bacteria stop skin cancer?," 28 Feb. 2018 Solution: The following morning, her stool test results showed a positive test for Clostridium difficile infection. Gul Madison, Philly.com, "Medical Mystery: What caused healthy woman's severe diarrhea, abdominal pain?," 12 Jan. 2018 Fecal transplants are already being used to treat stubborn colon infections of Clostridium difficile bacteria, notes immunotherapy researcher Alexandra Snyder of Memorial Sloan Kettering Cancer Center in New York City. Jocelyn Kaiser, Science | AAAS, "Your gut bacteria could determine how you respond to cutting-edge cancer drugs," 2 Nov. 2017 The incidence of C. difficile infection in England declined by 80 percent after 2006, when strict hospital sanitation and antibiotic prescription controls were both implemented. Nicholas Bakalar, New York Times, "Limiting Antibiotics Curbs Deadly Hospital Infections," 25 Jan. 2017 All three hospitals are worse than average on C. difficile infections, and deaths from serious treatable complications after surgery. Darla Carter, The Courier-Journal, "Loss or opportunity? Could hospitals improve without KentuckyOne Health?," 3 July 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'difficile.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of difficile

1536, in the meaning defined above

History and Etymology for difficile

borrowed from French, "difficult," going back to Middle French, borrowed from Latin difficilis — more at difficulty

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The first known use of difficile was in 1536

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