debilitating
adjective
                                                                                                                            
                                                            de·bil·i·tat·ing
                    
                                                                                                              
                                                                                                                                  di-ˈbi-lə-ˌtā-tiŋ 
                                                                                                                              
            dē-
                                                      
                                                          
                                
              
          
                                                      : causing serious impairment of strength or ability to function                                      
              
                             
debilitating pain
                                       a debilitating fear of public speaking
                                       a debilitating illness
                                       Thirty years have passed since a vaccine wiped out polio, but some of those who conquered the debilitating disease as children are now experiencing symptoms that seem all too familiar.—
Fay Knicely
                                       Several of these drugs are now in clinical testing to determine whether they can reduce or eliminate the debilitating nausea suffered by cancer patients on chemotherapy.—
Ron Cowen
                         
                
                    
                                                      debilitatingly
                                      adverb
                                                                                                      
                        
                        
    
          
         
                        Debilitatingly asthmatic as a child, Scarfe developed his talent while amusing himself and acquired the cynicism for authority that empowers his … drawings and sculpture during many frightening encounters with medical incompetence.    
        
        
            —
Ray Olson          
  
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  Merriam-Webster unabridged




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