cystic fibrosis

noun

Definition of cystic fibrosis

: a common, progressive hereditary disease of exocrine gland function that typically appears in infancy or early childhood and is marked by the accumulation of thick, sticky mucus in the ducts and passages of various organs and especially those of the lungs and pancreas resulting in shortness of breath, persistent cough, chronic respiratory infection, pancreatic enzyme insufficiency, faulty digestion, malnutrition, and poor growth

Note: The genetic mutation linked to cystic fibrosis causes disruption in the movement of chloride ions and water across cell membranes resulting in mucus that is thick and sticky instead of thin and slippery and in elevated concentrations of sodium and chloride in sweat and saliva. Cystic fibrosis occurs especially in people of northern European ancestry and is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene on a chromosome other than a sex chromosome.

… children with cystic fibrosis are born with healthy lungs; only later do their lungs become plugged with mucus and incur infections.The Journal of the American Medical Association Cystic fibrosis is the most common lethal inherited disorder in the United States. Approximately 30,000 people in this country have inherited two defective copies of the CF gene and thus the disease; approximately 1 in 20 Americans has just one copy of the gene and is a carrier of the disease.— Joe Palca abbreviation CF

Examples of cystic fibrosis in a Sentence

Recent Examples on the Web Detectives contacted the victim’s pediatrician who said there were concerns the child may have cystic fibrosis and that the medical office attempted to make contact with the parents numerous times. Amanda Rabines, Orlando Sentinel, 12 May 2022 Genetic diseases like sickle cell anemia or cystic fibrosis occur when a section of a chromosome or a single gene is defective or missing, and their effects are unmistakable. Anne Skomorowsky, WSJ, 5 May 2022 May is awareness month for arthritis, hepatitis, lupus, asthma and allergies, celiac disease, mental health, high blood pressure, preeclampsia and cystic fibrosis. Scott Lafee, San Diego Union-Tribune, 3 May 2022 The law prevents abortions from being performed, unless the matter is life-threatening, on fetuses with certain fetal abnormalities like Down syndrome or cystic fibrosis. Kyle Morris, Fox News, 15 Dec. 2021 Conrad works as a professional fundraiser for cystic fibrosis, while Ben works as an actuary. Steven Aquino, Forbes, 25 Apr. 2022 In addition to ulcerative colitis, some examples of other health conditions that occur more commonly in the Ashkenazi Jewish population include Tay-Sachs disease, Gaucher disease, and cystic fibrosis. Jill Seladi-schulman, SELF, 15 Feb. 2022 More than a dozen conditions — including leukemia, spina bifida, cystic fibrosis and rheumatoid arthritis — automatically qualify a student for the academy. Tracy Swartz, chicagotribune.com, 5 Aug. 2021 Kelly, 35, was diagnosed with cystic fibrosis as an infant and has never been healthy enough to work full time. Liz Szabo, CNN, 18 Mar. 2022 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cystic fibrosis.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of cystic fibrosis

1938, in the meaning defined above

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The first known use of cystic fibrosis was in 1938

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Dictionary Entries Near cystic fibrosis

cysticercus

cystic fibrosis

cystid

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Statistics for cystic fibrosis

Last Updated

22 Jun 2022

Cite this Entry

“Cystic fibrosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cystic%20fibrosis. Accessed 26 Jun. 2022.

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More Definitions for cystic fibrosis

cystic fibrosis

noun

Medical Definition of cystic fibrosis

: a common, progressive, hereditary disease of exocrine gland function that typically appears in infancy or early childhood and is marked by the accumulation of thick, sticky mucus in the ducts and passages of various organs and especially those of the lungs and pancreas resulting in shortness of breath, persistent cough, chronic respiratory infection, pancreatic enzyme insufficiency, faulty digestion, malnutrition, and poor growth

Note: The genetic mutation linked to cystic fibrosis causes disruption in the movement of chloride ions and water across cell membranes resulting in mucus that is thick and sticky instead of thin and slippery and in elevated concentrations of sodium and chloride in sweat and saliva. Cystic fibrosis occurs especially in people of northern European ancestry and is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene on a chromosome other than a sex chromosome.

called also fibrocystic disease of the pancreas, mucoviscidosis

abbreviation CF

More from Merriam-Webster on cystic fibrosis

Britannica.com: Encyclopedia article about cystic fibrosis

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