cystic fibrosis

noun

Definition of cystic fibrosis 

: a common hereditary disease that appears usually in early childhood, involves functional disorder of the exocrine glands, and is marked especially by difficulty in breathing due to mucus accumulation in airways, by faulty digestion due to a deficiency of pancreatic enzymes, and by excessive loss of salt in the sweat

Note: Cystic fibrosis occurs especially in Caucasian populations and is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene on a chromosome other than a sex chromosome.

Examples of cystic fibrosis in a Sentence

Recent Examples on the Web

Vertex balked, in part, because just 5 percent of cystic fibrosis patients are eligible for Kalydeco, but half are eligible for Orkambi. Ed Silverman, BostonGlobe.com, "Vertex, U.K. health officials at impasse over pricey cystic fibrosis drug," 5 July 2018 Now an athletic 29-year-old, Cote is putting his energy toward helping other cystic fibrosis patients fight for longer, healthier lives. Grant Butler, OregonLive.com, "West Linn murder victim 'loved wholeheartedly,' friends say," 10 Mar. 2018 The debate over Orkambi may soon become moot — earlier this year, the Food and Drug Administration approved a new cystic fibrosis drug, also made by Vertex. Katie Thomas, New York Times, "A Drug Costs $272,000 a Year. Not So Fast, Says New York State.," 24 June 2018 Both Cole and Haley play cystic fibrosis patients who fall in love while treated at the same hospital. Tamara Fuentes, Seventeen, "Here's the Real Reason Why Cole Sprouse Wasn't at the 2018 MTV Movie & TV Awards with Lili Reinhart," 17 June 2018 One of its fruits is Kalydeco, a drug for a mutation causing a small number of cases of cystic fibrosis. Bradley J. Fikes, sandiegouniontribune.com, "From cancer to genetic diseases, San Diego's march of drugs progresses," 10 June 2018 Of those, 122 had a primary diagnosis of cystic fibrosis. Jessica Ravitz, CNN, "Search for new lungs begins with changed heart," 23 May 2018 That’s the quandary over Orkambi, a drug that was approved in 2015 for cystic fibrosis and was only the second ever to address the underlying cause of the genetic disease. Katie Thomas, New York Times, "A Drug Costs $272,000 a Year. Not So Fast, Says New York State.," 24 June 2018 In effect, the agency was asking the company to provide Orkambi and its future cystic fibrosis drugs at no additional cost to the NHS. Ed Silverman, BostonGlobe.com, "Vertex, U.K. health officials at impasse over pricey cystic fibrosis drug," 5 July 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cystic fibrosis.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of cystic fibrosis

1938, in the meaning defined above

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Last Updated

26 Sep 2018

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The first known use of cystic fibrosis was in 1938

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More Definitions for cystic fibrosis

cystic fibrosis

noun

English Language Learners Definition of cystic fibrosis

medical : a very serious disease that usually appears in young children and that makes it hard to breathe and to digest food properly

cystic fibrosis

noun

Medical Definition of cystic fibrosis 

: a hereditary disease prevalent especially in Caucasian populations that appears usually in early childhood, is inherited as an autosomal recessive monogenic trait, involves functional disorder of the exocrine glands, and is marked especially by faulty digestion due to a deficiency of pancreatic enzymes, by difficulty in breathing due to mucus accumulation in airways, and by excessive loss of salt in the sweat

called also fibrocystic disease of the pancreas, mucoviscidosis

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