: an enzyme (such as adenylate cyclase) that catalyzes cyclization of a compound
Examples of cyclase in a Sentence
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Nitric oxide then activates an enzyme called guanylate cyclase, which increases cGMP production.
—
Amber Smith, Discover Magazine, 6 Nov. 2023
The drug candidate in the study works by blocking a protein called soluble adenylyl cyclase (SAC), which helps control sperm motility and movement.
—Alyssa Hui, Verywell Health, 23 Feb. 2023
The new drug targets a protein called soluble adenylyl cyclase (sAC), according to study lead author Melanie Balbach, postdoctoral fellow at Weill Cornell Medicine.
—Adrianna Rodriguez, USA TODAY, 16 Feb. 2023
Instead, the chronically constipated can opt for prescription medications like Trulance and Linzess, both guanylate cyclase-C agonists (GCC-agonists) and FDA approved.
—Lauren Sigfusson, Discover Magazine, 20 Dec. 2017
Tadalafil from the Launch Sequence supplements in the recall can interact with nitroglycerin or guanylate cyclase inhibitors that some people might take regularly.
—Chris Smith, BGR, 5 July 2022
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Amber Smith, Discover Magazine, 6 Nov. 2023
The drug candidate in the study works by blocking a protein called soluble adenylyl cyclase (SAC), which helps control sperm motility and movement.
—Alyssa Hui, Verywell Health, 23 Feb. 2023
The new drug targets a protein called soluble adenylyl cyclase (sAC), according to study lead author Melanie Balbach, postdoctoral fellow at Weill Cornell Medicine.
—Adrianna Rodriguez, USA TODAY, 16 Feb. 2023
Instead, the chronically constipated can opt for prescription medications like Trulance and Linzess, both guanylate cyclase-C agonists (GCC-agonists) and FDA approved.
—Lauren Sigfusson, Discover Magazine, 20 Dec. 2017
Tadalafil from the Launch Sequence supplements in the recall can interact with nitroglycerin or guanylate cyclase inhibitors that some people might take regularly.
—Chris Smith, BGR, 5 July 2022
Cite this Entry
“Cyclase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cyclase. Accessed 19 Jul. 2025.
Copy CitationMedical Definition
cyclase
noun
cy·clase
ˈsī-ˌklās, -ˌklāz 
: an enzyme (as adenyl cyclase) that catalyzes cyclization of a compound
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