cy·​clase ˈsī-ˌklās How to pronounce cyclase (audio)
: an enzyme (such as adenylate cyclase) that catalyzes cyclization of a compound

Examples of cyclase in a Sentence

Recent Examples on the Web The drug candidate in the study works by blocking a protein called soluble adenylyl cyclase (SAC), which helps control sperm motility and movement. Alyssa Hui, Verywell Health, 23 Feb. 2023 The new drug targets a protein called soluble adenylyl cyclase (sAC), according to study lead author Melanie Balbach, postdoctoral fellow at Weill Cornell Medicine. Adrianna Rodriguez, USA TODAY, 16 Feb. 2023 Instead, the chronically constipated can opt for prescription medications like Trulance and Linzess, both guanylate cyclase-C agonists (GCC-agonists) and FDA approved. Lauren Sigfusson, Discover Magazine, 20 Dec. 2017 Tadalafil from the Launch Sequence supplements in the recall can interact with nitroglycerin or guanylate cyclase inhibitors that some people might take regularly. Chris Smith, BGR, 5 July 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'cyclase.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


cycl- + -ase

First Known Use

1946, in the meaning defined above

Time Traveler
The first known use of cyclase was in 1946

Dictionary Entries Near cyclase

Cite this Entry

“Cyclase.” Dictionary, Merriam-Webster, Accessed 16 Apr. 2024.

Medical Definition


: an enzyme (as adenyl cyclase) that catalyzes cyclization of a compound
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