corticotropin

noun

cor·​ti·​co·​tro·​pin ˌkȯr-ti-kō-ˈtrō-pən How to pronounce corticotropin (audio)
variants or less commonly corticotrophin
: acth
also : a preparation of ACTH that is used especially in the treatment of rheumatoid arthritis and rheumatic fever

Examples of corticotropin in a Sentence

Recent Examples on the Web Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Neuroskeptic, Discover Magazine, 13 Apr. 2010 Ketamine relieves the depression of mice when it is administered by men but not by women, although the lack of efficacy in women’s administration can be corrected if the mice are injected with corticotropin-releasing hormone. Sophie Lewis, Harper’s Magazine , 26 Oct. 2022 And, some of these drugs have active ingredients that are very old, as is the case with Synthroid (levothyroxine), Makena (hydroxyprogesterone caproate), and Acthar Gel (corticotropin). Joshua Cohen, Forbes, 10 Oct. 2022 When a woman is chronically stressed, cortisol binds to receptors on the placenta, which then put out more corticotropin-releasing hormone, or CRH. Mark Johnson, Milwaukee Journal Sentinel, 23 Aug. 2021 Long Term: To start the HPA axis, the hypothalamus sends corticotropin-releasing hormone (CRH) to the pituitary gland. Bridget Alex, Discover Magazine, 21 June 2019 And experiments in rats and cultured cells show that corticotropin-releasing hormone, which the body releases in response to stress, also increases neuronal production of CGRP, Russo says. Emily Underwood, Science | AAAS, 18 May 2018 During abstinence from alcohol, stress neurotransmitters such as corticotropin-releasing factor (FRC) and dynorphin are released. Jamie Smolen, chicagotribune.com, 23 Dec. 2017

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'corticotropin.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1946, in the meaning defined above

Time Traveler
The first known use of corticotropin was in 1946

Dictionary Entries Near corticotropin

Cite this Entry

“Corticotropin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/corticotropin. Accessed 15 Oct. 2024.

Medical Definition

corticotropin

noun
cor·​ti·​co·​tro·​pin -ˈtrō-pən How to pronounce corticotropin (audio)
variants also corticotrophin
: acth
also : a preparation of ACTH that is used especially in the treatment of rheumatoid arthritis and rheumatic fever

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