confluence

noun

con·​flu·​ence ˈkän-ˌflü-ən(t)s  kən-ˈflü- 

1

: a coming or flowing together, meeting, or gathering at one point

At the confluence of Native American, Hispanic, and Anglo cultures, Santa Fe is the symbolic heart of the Southwest.

—Jeffrey Steingarten

A hip urban confluence of tasting rooms, galleries, and surfboard designers, it's a place where wine, art and beach culture coalesce.

—Wine Enthusiast Magazine

Every once in a while in pop music there is a magical confluence: the right performers doing the right music with the right support.

—Ralph Novak

Italian influences have marked not only the style of architecture in Passau but also the way of life. Then, of course, Eastern Europe is next door. There are many confluences, it seems.

—N. Scott Momaday

2

a

: the flowing together of two or more streams

A complex lacework of waterways formed by the confluence of the Sacramento and San Joaquin rivers, the delta is the state's major water source …

—Robert B. Gunnison

Confluences are a basic building block of river networks on all scales.

—Chris Paola

b

: the place of meeting of two streams

… quaint Carbondale is set at the confluence of the Crystal and Roaring Fork Rivers.

—National Geographic

c

: the stream or body formed by the junction of two or more streams : a combined flood

… and eventually chose, disastrously, the only place in Assam where it was impossible for tea to thrive, being regularly drowned by the confluence of two huge rivers, a more suitable terrain for rice.

—Christian Lamb

3

or confluency

kən-ˈflü-ən(t)-sē 

cell biology : the degree of substrate coverage that is exhibited by proliferating, adherent cells cultured in a laboratory vessel (such as a petri dish or flask)

At days 12-14, cell confluence reached 80%.

—Runguang Li et al.

The measurement of cell confluency is used to determine the growth phase of cells …

—Mee Foong et al.

also : complete coverage of a culture substrate by proliferating, adherent cells

When the cells reach confluence, they form aggregates and can be serially cultured.

—C. A. B. Jahoda et al.

Replicate dishes of pooled cells were grown to confluency and induced with Newcastle disease virus …

—Hermann Ragg and Charles Weissmann

Did you know?

The joining of rivers—as at Harpers Ferry, West Virginia, where the Shenandoah and Potomac Rivers flow together spectacularly—was the original meaning of confluence, and in its later meanings we still hear a strong echo of the physical merging of waters. So today we can speak of a confluence of events, a confluence of interests, a confluence of cultures, and so on, from which something important often emerges.

Synonyms

• conjunction
• convergence
• convergency
• meeting

Examples of confluence in a Sentence

the Mississippi River's confluence with the Missouri River

a happy confluence of beautiful weather and spectacular scenery during our vacation

Recent Examples on the Web

Sheffield Castle once stood at the confluence of two rivers in the north England city, surviving for centuries until it was repurposed in the 17th and 18th centuries as part of the Industrial Revolution, according to the University of Sheffield. —Irene Wright, Miami Herald, 17 June 2025

There has also been a confluence of the pro-housing and anti-tourism struggles in Spain, whose 48 million residents welcomed a record 94 million international visitors last year. —Joseph Wilson, Los Angeles Times, 16 June 2025

Harper’s Ferry, West Virginia The site of John Brown’s raid in 1859 — a pivotal event in the fight against slavery, Harper’s Ferry is a small hamlet located at the confluence of the Potomac and Shenandoah rivers. —Noreen Kompanik, Boston Herald, 15 June 2025

But a confluence of developments triggered by Hamas' Oct. 7, 2023, attack -- plus the reelection of U.S. President Donald Trump -- created the conditions that allowed Israel to finally follow through on its threats. —Arkansas Online, 13 June 2025

Word History

Etymology

see confluent entry 1

First Known Use

15th century, in the meaning defined at sense 1

Kids Definition

confluence

noun

con·​flu·​ence ˈkän-ˌflü-ən(t)s  kən-ˈflü- 

1

: a coming together to one place

2

: a flowing together or place of meeting especially of streams