colony-stimulating factor

noun

col·​o·​ny-stim·​u·​lat·​ing factor ˈkä-lə-nē-ˈstim-yə-ˈlā-tiŋ How to pronounce colony-stimulating factor (audio)
: any of several glycoproteins that promote the differentiation of stem cells especially into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture

Example Sentences

Recent Examples on the Web Giving mice a drug that blocked the critical protein colony-stimulating factor 1, which microglia need to survive, was shown to remove around 90 percent of microglia in the brain. Jason Ulrich, Scientific American, 1 Aug. 2021 Otilimab is a monoclonal antibody against the granulocyte macrophage colony-stimulating factor, or GM-CSF, which stimulates the production of white blood cells. Matthew Herper, STAT, 27 Feb. 2021 The virus, called T-VEC, produces a substance called granulocyte macrophage colony-stimulating factor. Bradley J. Fikes, sandiegouniontribune.com, 7 Sep. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'colony-stimulating factor.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

First Known Use

1967, in the meaning defined above

Time Traveler
The first known use of colony-stimulating factor was in 1967

Dictionary Entries Near colony-stimulating factor

Cite this Entry

“Colony-stimulating factor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/colony-stimulating%20factor. Accessed 31 Jan. 2023.

Medical Definition

colony-stimulating factor

noun
col·​o·​ny-stim·​u·​lat·​ing factor -ˌstim-yə-ˌlāt-iŋ- How to pronounce colony-stimulating factor (audio)
: any of several glycoproteins that promote the differentiation of stem cells especially into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture see granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, interleukin-3, macrophage colony-stimulating factor

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