colony-stimulating factor

noun

col·​o·​ny-stim·​u·​lat·​ing factor ˈkä-lə-nē-ˈstim-yə-ˈlā-tiŋ How to pronounce colony-stimulating factor (audio)
: any of several glycoproteins that promote the differentiation of stem cells especially into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture

Examples of colony-stimulating factor in a Sentence

Recent Examples on the Web Giving mice a drug that blocked the critical protein colony-stimulating factor 1, which microglia need to survive, was shown to remove around 90 percent of microglia in the brain. Jason Ulrich, Scientific American, 1 Aug. 2021 Otilimab is a monoclonal antibody against the granulocyte macrophage colony-stimulating factor, or GM-CSF, which stimulates the production of white blood cells. Matthew Herper, STAT, 27 Feb. 2021 The virus, called T-VEC, produces a substance called granulocyte macrophage colony-stimulating factor. Bradley J. Fikes, sandiegouniontribune.com, 7 Sep. 2017

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'colony-stimulating factor.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1967, in the meaning defined above

Time Traveler
The first known use of colony-stimulating factor was in 1967

Dictionary Entries Near colony-stimulating factor

Cite this Entry

“Colony-stimulating factor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/colony-stimulating%20factor. Accessed 27 May. 2024.

Medical Definition

colony-stimulating factor

noun
col·​o·​ny-stim·​u·​lat·​ing factor -ˌstim-yə-ˌlāt-iŋ- How to pronounce colony-stimulating factor (audio)
: any of several glycoproteins that promote the differentiation of stem cells especially into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture see granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, interleukin-3, macrophage colony-stimulating factor

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