: an antihypertensive drug C9H9Cl2N3 used especially to treat essential hypertension, to prevent migraine headache, and to diminish opioid and nicotine withdrawal symptoms

Examples of clonidine in a Sentence

Recent Examples on the Web
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At the time of their interview, Clancy was taking antipsychotic and anti-anxiety medications including olanzapine (brand name Zyprexa), bupropion (brand name Wellbutrin), clonidine and propranolol, Mack said. — N'dea Yancey-Bragg, USA Today, 24 Aug. 2026 Ferro noted that medetomidine withdrawal often requires much higher than typical doses of clonidine. — Hannah Harris Green, STAT, 26 June 2026 Additionally, authorities said the prescription medication clonidine was found in her system despite not having been prescribed to her, per the statement. — Nicole Acosta, PEOPLE, 24 June 2026 The most common blood pressure medications that can cause this are beta blockers and clonidine. — Jessica Swirble, Verywell Health, 8 June 2026 See All Example Sentences for clonidine

Word History

Etymology

chlor- + aniline + imide + -ine entry 2

First Known Use

1969, in the meaning defined above

Time Traveler
The first known use of clonidine was in 1969

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Cite this Entry

“Clonidine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/clonidine. Accessed 24 Sep. 2026.

Medical Definition

: an antihypertensive drug used in the form of its hydrochloride C9H9Cl2N3·HCl especially to treat essential hypertension, to prevent migraine headache, and to diminish opiate withdrawal symptoms

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