clinical trial

noun

: a scientifically controlled study of the safety and effectiveness of a therapeutic agent (such as a drug or vaccine) using consenting human subjects

Examples of clinical trial in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Recent large-scale analyses, including a 2024 review in Neuro-Oncology, suggest that median survival has improved only marginally in the last decade despite hundreds of clinical trials. Lauryn Higgins, Flow Space, 11 Dec. 2025 The drug, developed in partnership with Roche, has shown more moderate side effects than current injectables in early-stage clinical trials. Elsa Ohlen, CNBC, 11 Dec. 2025 As with all drugs approved by the FDA, these medications were extensively tested in clinical trials for safety and efficacy before they were given the green light. Tanya Lewis, Scientific American, 9 Dec. 2025 The first clinical trials in this model will begin soon. Nancy Walecki, The Atlantic, 8 Dec. 2025 See All Example Sentences for clinical trial

Word History

First Known Use

1946, in the meaning defined above

Time Traveler
The first known use of clinical trial was in 1946

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Cite this Entry

“Clinical trial.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/clinical%20trial. Accessed 13 Dec. 2025.

Medical Definition

clinical trial

noun
: a scientifically controlled study of the safety and effectiveness of a therapeutic agent (as a drug or vaccine) using consenting human subjects

More from Merriam-Webster on clinical trial

Last Updated: - Updated example sentences
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