clinical trial


Definition of clinical trial

: a scientifically controlled study of the safety and effectiveness of a therapeutic agent (such as a drug or vaccine) using consenting human subjects

Examples of clinical trial in a Sentence

Recent Examples on the Web

Hundreds of clinical trials have failed, and some advances once thought to be promising have turned into dead ends., "AARP invests $60M to fund research for cures to dementia and Alzheimer's," 25 June 2018 According to the Cancer Research Institute, six types of immunotherapy clinical trials are taking aim at leukemia. Ankur Parikh, STAT, "We need more answers about immunotherapy for the elderly," 22 June 2018 For women everywhere Purdue researchers are looking for companies with technological expertise to further develop its app and complete its third phase of clinical trials. Sonja Haller, USA TODAY, "This app could help pregnant women predict whether they'll develop preeclampsia," 23 May 2018 More than 80 percent of clinical trials for human patients fail; for cancer, the failure rate is 90 percent. Amy Sutherland,, "An experimental cancer treatment cured this dog. Could it work for people?," 16 May 2018 The therapies often work in a variety of cancer subsets, triggering a rush of clinical trials as companies jostle for market share. Scientific American, "After the Gold Rush," 3 May 2018 At that advisory committee meeting two years ago, one woman said that her grandmother had been part of the clinical trials for the drug and that Nuplazid had been life-changing. Blake Ellis And Melanie Hicken, CNN, "FDA re-examines safety of controversial new drug," 25 Apr. 2018 And after that happened, its papers—reports, reviews, and meta-analysis of clinical trials—all disappeared. Sarah Scoles, WIRED, "What Happens When Science Just Disappears?," 25 Apr. 2018 Two rounds of clinical trials bolstered its safety record in humans. Melissa Healy,, "Could this drug help the brain recover after a stroke?," 6 Apr. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'clinical trial.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of clinical trial

1946, in the meaning defined above

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Last Updated

11 Apr 2019

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The first known use of clinical trial was in 1946

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clinical trial


Medical Definition of clinical trial

: a scientifically controlled study of the safety and effectiveness of a therapeutic agent (as a drug or vaccine) using consenting human subjects

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