cimetidine

noun

ci·​met·​i·​dine sī-ˈme-tə-ˌdēn 

: a histamine analog C₁₀H₁₆N₆S that inhibits gastric acid secretion and is used especially in the treatment of duodenal ulcers

Examples of cimetidine in a Sentence

Recent Examples on the Web

Sucralfates Histamine receptor antagonist (H2RAs) such as cimetidine and ranitidine. —Emmanuella Ogbonna, Health, 23 Aug. 2025

Researchers offering case reports of success with cimetidine against shingles have called for robust clinical trials. —Joe and Teresa Graedon, oregonlive, 29 May 2023

Alternative histamine blockers like famotidine (Pepcid) and cimetidine (Tagamet) have so far not been found to contain NDMA, Dr. Smith said, and neither has Prilosec nor other proton pump inhibitors. —Christina Caron, New York Times, 18 Apr. 2020

To date, the FDA's testing has not found NDMA in famotidine (Pepcid), cimetidine (Tagamet), esomeprazole (Nexium), lansoprazole (Prevacid) or omeprazole (Prilosec). —USA TODAY, 1 Apr. 2020

Other heartburn medications, such as famotidine (Pepcid), cimetidine (Tagamet), esomeprazole (Nexium), lansoprazole (Prevacid) and omeprazole (Prilosec) have not tested positive for signs of NDMA. —NBC News, 20 Jan. 2020

Word History

Etymology

ci- (alteration of cyan-) + methyl + -idine

First Known Use

1975, in the meaning defined above

Rhymes for cimetidine

• acetylene
• adenosine
• amphetamine
• anthropocene
• antipyrine
• apomorphine
• apoprotein
• aquamarine
• arsphenamine
• azobenzene
• buprenorphine
• chlorobenzene

Medical Definition

cimetidine

noun

ci·​met·​i·​dine sī-ˈmet-ə-ˌdēn 

: an H₂ antagonist C₁₀H₁₆N₆S that like histamine contains the ring structure of imidazole and is used to inhibit gastric acid secretion in conditions in which such secretion produces duodenal or gastric ulcers or erosive lesions (as in serious cases of gastroesophageal reflux disease) see tagamet