ci·​met·​i·​dine sī-ˈme-tə-ˌdēn How to pronounce cimetidine (audio)
: a histamine analog C10H16N6S that inhibits gastric acid secretion and is used especially in the treatment of duodenal ulcers

Examples of cimetidine in a Sentence

Recent Examples on the Web The authors cite a study using 400 milligrams of cimetidine three times daily, which is much higher than the heartburn dose. Joe and Teresa Graedon, oregonlive, 29 May 2023 Researchers offering case reports of success with cimetidine against shingles have called for robust clinical trials. Joe and Teresa Graedon, oregonlive, 29 May 2023 An article in the Journal of the American Podiatric Medical Association (November 1995) reported several anecdotal reports of success with cimetidine (Tagamet). Joe Graedon, M.s., and Teresa Graedon, oregonlive, 13 Mar. 2023 Are there any problems taking cimetidine occasionally? Dr. Keith Roach, oregonlive, 2 June 2022 For example, there is some benefit to the medicine cimetidine, normally used as an antacid treatment. Dr. Keith Roach, oregonlive, 8 June 2021 Alternative histamine blockers like famotidine (Pepcid) and cimetidine (Tagamet) have so far not been found to contain NDMA, Dr. Smith said, and neither has Prilosec nor other proton pump inhibitors. Christina Caron, New York Times, 18 Apr. 2020 To date, the FDA's testing has not found NDMA in famotidine (Pepcid), cimetidine (Tagamet), esomeprazole (Nexium), lansoprazole (Prevacid) or omeprazole (Prilosec). USA TODAY, 1 Apr. 2020 Other heartburn medications, such as famotidine (Pepcid), cimetidine (Tagamet), esomeprazole (Nexium), lansoprazole (Prevacid) and omeprazole (Prilosec) have not tested positive for signs of NDMA. NBC News, 20 Jan. 2020

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'cimetidine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


ci- (alteration of cyan-) + methyl + -idine

First Known Use

1975, in the meaning defined above

Time Traveler
The first known use of cimetidine was in 1975

Dictionary Entries Near cimetidine

Cite this Entry

“Cimetidine.” Dictionary, Merriam-Webster, Accessed 14 Jul. 2024.

Medical Definition


ci·​met·​i·​dine sī-ˈmet-ə-ˌdēn How to pronounce cimetidine (audio)
: an H2 antagonist C10H16N6S that like histamine contains the ring structure of imidazole and is used to inhibit gastric acid secretion in conditions in which such secretion produces duodenal or gastric ulcers or erosive lesions (as in serious cases of gastroesophageal reflux disease) see tagamet

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