chemistry

noun

chem·​is·​try ˈke-mə-strē How to pronounce chemistry (audio)
plural chemistries
1
: a science that deals with the composition, structure, and properties of substances and with the transformations that they undergo
2
a
: the composition and chemical properties of a substance
the chemistry of iron
b
: chemical processes and phenomena (as of an organism)
blood chemistry
3
a
: a strong mutual attraction, attachment, or sympathy
they have a special chemistry
b
: interaction between people working together
specifically : such interaction when harmonious or effective
a team lacking chemistry

Examples of chemistry in a Sentence

studying the chemistry of gasoline They tried dating, but there was no chemistry between them. the chemistry of the office
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Take 25 Hours, in Long Island City, for example, which is freighted with a depressing ambience that is equal parts chemistry lab and subterranean grotto. Vince Aletti, New Yorker, 17 Apr. 2026 With former members Barnard and Scott Tuma (who contributed those subterranean guitar textures to Souled’s ’90s albums) long gone from the lineup, Sanctions thrives on the singular chemistry between Grigoroff and Adducci. Zach Schonfeld, Pitchfork, 17 Apr. 2026 In a surprising twist, the team stumbled upon a recipe so straightforward it could be replicated in a high school chemistry lab. Mrigakshi Dixit, Interesting Engineering, 17 Apr. 2026 The redshirt junior quarterback spent the spring working with his new teammates and building chemistry. Adam Lichtenstein, Sun Sentinel, 17 Apr. 2026 See All Example Sentences for chemistry

Word History

Etymology

earlier chymistrie, chymistrie, from chymist, chimist chemist + -ry, probably after earlier alchemistri, alcumistry "alchemy"

Note: Regarding distinctions between chemistry and alchemy see note at chemist.

First Known Use

1646, in the meaning defined at sense 1

Time Traveler
The first known use of chemistry was in 1646

Browse Nearby Words

Cite this Entry

“Chemistry.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/chemistry. Accessed 23 Apr. 2026.

Kids Definition

chemistry

noun
chem·​is·​try ˈkem-ə-strē How to pronounce chemistry (audio)
1
: a science that deals with the composition, structure, and properties of substances and with the changes that they go through
2
: chemical composition, properties, or processes
the chemistry of gasoline
the chemistry of iron
the chemistry of blood
chemist
-əst
noun
Etymology

an altered form of obsolete chimistry, chymistry "alchemy," derived from Latin alchimista "alchemist," from alchymia "alchemy," from Arabic al-kīmiyā' (same meaning), from al "the" and kīmiyā' "alchemy," from Greek chēmeia "alchemy" — related to alchemy, chemo-

Medical Definition

chemistry

noun
chem·​is·​try ˈkem-ə-strē How to pronounce chemistry (audio)
plural chemistries
1
: a science that deals with the composition, structure, and properties of substances and of the transformations that they undergo
2
a
: the composition and chemical properties of a substance
the chemistry of hemoglobin
b
: chemical processes and phenomena (as of an organism)
blood chemistry

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