ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

ˈser-

plural ceramides

: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids

The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.

—L. Stivitz

Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.

—Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web

The specially emulsified formula keeps the ceramides evenly dispersed (no shaking required), while the lightweight mist feels especially refreshing on hot, humid summer days. — Christa Joanna Lee, Allure, 23 June 2026

This hydrogel mask is our favorite because it’s packed with skin-plumping ingredients like snail mucin and ceramides to address dehydration and dryness. — Alanna Martine Kilkeary, Glamour, 22 June 2026

Instead of merely offering sun protection, Oska says that modern formulas target common signs of aging—including dryness, uneven tone, and dullness—with ingredients like hyaluronic acid, ceramides, squalane, and peptides. — Jenny Berg, Vogue, 22 June 2026

Formulated with a skin barrier complex, ceramides, Bakuchiol, and niacinamide, the mask deeply nourishes and hydrates, resulting in plumper, smoother skin by morning. — Erika Reals, InStyle, 19 June 2026

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Rhymes for ceramide

• actinide
• aldehyde
• alkoxide
• alongside
• amplified
• arsenide
• beautified
• biocide
• bisulphide
• butoxide
• calcified
• certified

Medical Definition

ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue