ceramide

noun

cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.L. Stivitz
Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web
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This longer-lasting formula is made with aluminum, botanical scents like cucumber and pear, and ceramides—the trifecta for hardworking armpits. Sara Coughlin, SELF, 23 July 2025 In addition to sun-protecting minerals, the formula contains hyaluronic acid and three different ceramides, which help moisturize and support the skin’s natural barrier. Brigitt Earley, Glamour, 23 July 2025 Hyaluronic acid, ceramides, niacinamide, peptides, and panthenol to repair the skin barrier and add moisture. Larry Stansbury, Essence, 14 July 2025 The emphasis isn’t just on styling but on truly restoring scalp and strand health with ingredients often found in skincare—think collagen, ceramides, and botanical oils. Conçetta Ciarlo, Vogue, 11 July 2025 See All Example Sentences for ceramide

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of ceramide was in 1958

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Cite this Entry

“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 30 Jul. 2025.

Medical Definition

ceramide

noun
cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue

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