ceramide
noun
cer·amide
ˈsir-ə-ˌmīd 
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.—
L. Stivitz
L. StivitzMoisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.—Constance Cardozo
Constance CardozoExamples of ceramide in a Sentence
Recent Examples on the Web
Niacinamide and tranexamic acid even tone and refine the look of pores, while ceramides, cholesterol, and peptides support the barrier—so skin looks smoother, brighter, and more refreshed in under 30 minutes.
—Christa Joanna Lee, Allure, 26 Mar. 2026
The formula also includes ceramides that help restore the barrier, which is often compromised in eczema-prone skin.
—Hana Hong, Glamour, 25 Mar. 2026
Tronque’s formula harnesses green coffee and caffeine to help support skin elasticity, while Cyklar’s blend leans into barrier care with ceramides, urea, and squalane.
—Conçetta Ciarlo, Vogue, 23 Mar. 2026
Over-the-counter supplements such as fish oil, ceramides, hyaluronic acid, probiotics, and other multivitamins can help improve moisture and relieve dry skin.
—Ayesha Gulzar, Verywell Health, 10 Mar. 2026
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Christa Joanna Lee, Allure, 26 Mar. 2026
The formula also includes ceramides that help restore the barrier, which is often compromised in eczema-prone skin.
—Hana Hong, Glamour, 25 Mar. 2026
Tronque’s formula harnesses green coffee and caffeine to help support skin elasticity, while Cyklar’s blend leans into barrier care with ceramides, urea, and squalane.
—Conçetta Ciarlo, Vogue, 23 Mar. 2026
Over-the-counter supplements such as fish oil, ceramides, hyaluronic acid, probiotics, and other multivitamins can help improve moisture and relieve dry skin.
—Ayesha Gulzar, Verywell Health, 10 Mar. 2026
See All Example Sentences for ceramide
Cite this Entry
“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 2 Apr. 2026.
Copy CitationMedical Definition
ceramide
noun
cer·amide
ˈsir-ə-ˌmīd
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue
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