ceramide
noun
cer·amide
ˈsir-ə-ˌmīd 
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.—
L. Stivitz
L. StivitzMoisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.—Constance Cardozo
Constance CardozoExamples of ceramide in a Sentence
Recent Examples on the Web
Take a look at the ingredients list for lightweight oils and butters, soothing aloe vera, and hydrating ceramides.
—Ariana Yaptangco, Glamour, 18 May 2026
In addition to being super hydrating, it’s made with three essential ceramides that help repair the skin barrier over time, which makes my skin feel soft and supple all day and night.
—Clara McMahon, PEOPLE, 13 May 2026
It’s also stacked with reliable tone-evening ingredients like tranexamic acid, niacinamide, and arbutin, plus supportive ingredients like ceramides, panthenol, and hyaluronic acid to keep skin hydrated and balanced.
—Christa Joanna Lee, Allure, 9 May 2026
The enzyme specifically helps break down a molecule called glucocerebroside — a component of the membrane surrounding cells — into glucose and ceramide so the parts can be reused.
—Samantha Agate, Fort Worth Star-Telegram, 6 May 2026
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Ariana Yaptangco, Glamour, 18 May 2026
In addition to being super hydrating, it’s made with three essential ceramides that help repair the skin barrier over time, which makes my skin feel soft and supple all day and night.
—Clara McMahon, PEOPLE, 13 May 2026
It’s also stacked with reliable tone-evening ingredients like tranexamic acid, niacinamide, and arbutin, plus supportive ingredients like ceramides, panthenol, and hyaluronic acid to keep skin hydrated and balanced.
—Christa Joanna Lee, Allure, 9 May 2026
The enzyme specifically helps break down a molecule called glucocerebroside — a component of the membrane surrounding cells — into glucose and ceramide so the parts can be reused.
—Samantha Agate, Fort Worth Star-Telegram, 6 May 2026
See All Example Sentences for ceramide
Cite this Entry
“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 21 May. 2026.
Copy CitationMedical Definition
ceramide
noun
cer·amide
ˈsir-ə-ˌmīd
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue
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