blood-brain barrier

noun
\ ˈbləd-ˈbrān- How to pronounce blood-brain barrier (audio) \

Definition of blood-brain barrier

: a naturally occurring barrier created by the modification of brain capillaries (as by reduction in fenestration and formation of tight cell-to-cell contacts) that prevents many substances from leaving the blood and crossing the capillary walls into the brain tissues

Examples of blood-brain barrier in a Sentence

Recent Examples on the Web In the brain, P-glycoprotein is present at high levels at the junction points, or the blood-brain barrier, between neurons and the dense network of blood vessels surrounding them. Dallas News, 29 June 2021 Ultrasound is used to open the blood-brain barrier in medical procedures, and acoustic stimulation of the aforementioned anatomical areas could produce symptoms consistent with AHIs. Beth Mole, Ars Technica, 3 Feb. 2022 These metals also have the ability to cross the blood-brain barrier, a feature of the human nervous system that defends the brain from pathogens and toxins in the blood, according to a 2015 study. Sudiksha Kochi, USA TODAY, 26 Jan. 2022 The same protein may be able to whisper its chemical message across the notoriously choosy blood-brain barrier and trigger anti-inflammatory processes in the brain. Emily Willingham, Scientific American, 8 Dec. 2021 Because of their molecular structure, endorphins cannot cross the blood-brain barrier. Outside Online, 7 Apr. 2021 The team also found that clusterin readily attached to the cells that form the blood-brain barrier. Emily Willingham, Scientific American, 8 Dec. 2021 Researchers have found signs that the virus can establish a foothold of sorts on the periphery of the brain, where the protective blood-brain barrier opens up to allow key molecules to slip through. Amina Khan Staff Writer, Los Angeles Times, 5 Nov. 2021 Due to the blood-brain barrier, biomarkers couldn’t be found in sufficient quantities. Tribune News Service, oregonlive, 25 Nov. 2021 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'blood-brain barrier.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of blood-brain barrier

1934, in the meaning defined above

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Time Traveler for blood-brain barrier

Time Traveler

The first known use of blood-brain barrier was in 1934

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Dictionary Entries Near blood-brain barrier

blood-borne

blood-brain barrier

blood brother

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Cite this Entry

“Blood-brain barrier.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/blood-brain%20barrier. Accessed 25 Jun. 2022.

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More Definitions for blood-brain barrier

blood-brain barrier

noun

Medical Definition of blood-brain barrier

: a naturally occurring barrier created by the modification of brain capillaries (as by reduction in fenestration and formation of tight cell-to-cell contacts) that prevents many substances from leaving the blood and crossing the capillary walls into the brain tissues abbreviation BBB

More from Merriam-Webster on blood-brain barrier

Britannica.com: Encyclopedia article about blood-brain barrier

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