Definition of belladonna
1
: an Old World poisonous plant (Atropa belladonna) of the nightshade family having purple or green bell-shaped flowers, glossy black berries, and root and leaves that yield atropine
— called also deadly nightshade
2
: a medicinal extract (such as atropine) from the belladonna plant
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Merriam-Webster unabridged
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Time Traveler for belladonna
The first known use of belladonna was in 1597
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