as·​par·​tame | \ ˈa-spər-ˌtām How to pronounce aspartame (audio) , ə-ˈspär-ˌtām How to pronounce aspartame (audio) \

Definition of aspartame

: a crystalline compound C14H18N2O5 that is a diamide synthesized from phenylalanine and aspartic acid and that is used as a low-calorie sweetener

Examples of aspartame in a Sentence

Recent Examples on the Web Plus, this green pick avoids the surprising additions found in many common toothpastes—like artificial sweeteners—in favor of organic stevia extract (rather than aspartame), to keep a pleasant taste without potentially spiking your blood sugar. Braelyn Wood,, "Olivia Wilde's Secret for Whiter Teeth Is This $6 Toothpaste from Walmart," 22 Nov. 2019 With artificial sweeteners—and if so, sucralose or aspartame? Zeynep Tufekci, Scientific American, "More Data Don’t Necessarily Help You Make Small Decisions," 1 Mar. 2019 The tangerine tango and mojito lime flavors — all aspartame-free — will make your evening commute feel slightly more tropical. Caroline Picard, Good Housekeeping, "The 8 Best Breath Mints to Carry Around With You All Day," 7 Dec. 2018 Several concerns by researchers have been raised about high-intensity sweeteners—saccharin and aspartame—and cancer. Jamie Pitlick, Quartzy, "The best and worst sugar substitutes for your health," 3 July 2019 The side effects of artificial and all-natural replacements like stevia, Truvia, Splenda, and, yes, aspartame are often questionable, and so the pursuit of that perfect sugarless dream continues. Jean Nick, Good Housekeeping, "How Safe Is The Newest "Natural" Sugar Substitute?," 16 Sep. 2015 And even the most organic of eaters can sometimes reach for conventional breath mints in the name of fast freshness—ending up with a mouthful of artificial sweeteners, such as aspartame and saccharin. Kris Rile, Good Housekeeping, "7 Best Breath Mints That Aren't Packed With Chemicals," 12 July 2017 Researchers fed groups of rats diets high in sugar or artificial sweeteners including aspartame and acesulfame potassium. Brett Molina, USA TODAY, "Artificial sweeteners can still lead to obesity and diabetes, study claims," 23 Apr. 2018 Also called nonnutritive sweeteners, these can be synthetic, such as saccharin and aspartame, or naturally derived, such as stevia. Eunice Zhang, Washington Post, "Diet drinks may seem like a good idea, but their effects may surprise you," 3 June 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'aspartame.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of aspartame

1972, in the meaning defined above

History and Etymology for aspartame

aspartic acid + phenylalanine + methyl + ester

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Time Traveler for aspartame

Time Traveler

The first known use of aspartame was in 1972

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Statistics for aspartame

Last Updated

27 Nov 2019

Cite this Entry

“Aspartame.” The Dictionary, Merriam-Webster Inc., Accessed 10 December 2019.

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More Definitions for aspartame


as·​par·​tame | \ ˈas-pər-ˌtām How to pronounce aspartame (audio) , ə-ˈspär- How to pronounce aspartame (audio) \

Medical Definition of aspartame

: a crystalline dipeptide ester C14H18N2O5 that is synthesized from the amino acids phenylalanine and aspartic acid and is used as a low-calorie sweetener — see nutrasweet

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What made you want to look up aspartame? Please tell us where you read or heard it (including the quote, if possible).


to state or do over again or repeatedly

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