aromatase

noun
aro·​ma·​tase | \ ə-ˈrō-mə-ˌtās How to pronounce aromatase (audio) , -ˌtāz \

Definition of aromatase

: an enzyme or complex of enzymes that promotes the conversion of an androgen into estrogen

Examples of aromatase in a Sentence

Recent Examples on the Web All participants were given standard hormone therapy (an aromatase inhibitor or tamoxifen) as well as a medication that shuts down the ovaries' production of estrogen. Samantha Lauriello, Health.com, "A New Breast Cancer Treatment Can Extend the Lives of Younger Patients, Study Finds," 4 June 2019 All of the women were given standard hormonal therapy -- an aromatase inhibitor or tamoxifen -- plus a medication that shuts down the ovaries' production of estrogen. Amy Norton, CBS News, "Newer drug extends lives of young breast cancer patients, study finds," 3 June 2019 But the effect that’s best understood is fat tissue’s ability to convert circulating steroids into estrogen via the enzyme aromatase, Dr. Jensen explains. Sarah Jacoby, SELF, "The Science on Weight and Health," 26 June 2018 According to the World Anti-Doping Agency, letrozole is an aromatase inhibitor that can act as a hormonal and metabolic stimulant by increasing testosterone concentration. Bianca Britton, CNN, "Tennis player Sara Errani 'disgusted' by doping ban increase," 12 June 2018 This happened, the group theorized, because AMH damped down levels of aromatase, an enzyme in the placenta that usually converts testosterone to a form of estrogen. Jennifer Couzin-frankel, Science | AAAS, "Scientists may be closer to understanding a mysterious but common cause of female infertility," 14 May 2018 Even after anti-estrogen treatments, known as aromatase inhibitors, were introduced as part of the regimen in recent decades, they were simply added on to chemotherapy. Alice Park, Time, "More Women With Breast Cancer May Soon Be Skipping Chemo. Here’s Why," 7 June 2018 With aromatase activity curtailed, extra testosterone snuck through and bathed the mouse fetuses in a PCOS-conducive environment. Jennifer Couzin-frankel, Science | AAAS, "Scientists may be closer to understanding a mysterious but common cause of female infertility," 14 May 2018 Her discovery, a drug called an aromatase inhibitor, was made up in batches at the University of Maryland in downtown Baltimore. baltimoresun.com, "Notable Maryland deaths in 2017," 20 Dec. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'aromatase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of aromatase

1959, in the meaning defined above

History and Etymology for aromatase

aromat(ize) + -ase

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Time Traveler for aromatase

Time Traveler

The first known use of aromatase was in 1959

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Statistics for aromatase

Last Updated

3 Sep 2020

Cite this Entry

“Aromatase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/aromatase. Accessed 29 Sep. 2020.

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More Definitions for aromatase

aromatase

noun
aro·​ma·​tase | \ ə-ˈrō-mə-ˌtās, -ˌtāz How to pronounce aromatase (audio) \

Medical Definition of aromatase

: an enzyme or complex of enzymes that promotes the conversion of an androgen (as testosterone) into estrogens (as estradiol)

Comments on aromatase

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