antibody

noun

an·​ti·​body ˈan-ti-ˌbä-dē How to pronounce antibody (audio)
: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

Examples of antibody in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
These included an anti-HIV antibody, a GLP-1-like peptide used for type 2 diabetes, and leptin, which regulates appetite. Aamir Khollam, Interesting Engineering, 27 Mar. 2026 The shot produces protective antibodies that are transmitted to the tick upon biting a vaccinated person, preventing the bacteria from spreading from tick to human host. Janet Loehrke, USA Today, 25 Mar. 2026 The high number of mutations may be helping the variant evade protection from vaccination or from prior infections, which prompt the immune system to produce defensive antibodies. Tom Gavin, EverydayHealth.com, 25 Mar. 2026 DeGeorge had some antibodies in his blood that meant the surgical team had to carefully monitor medications, temperature changes and other variables during the procedure. Kerry Breen, CBS News, 21 Mar. 2026 See All Example Sentences for antibody

Word History

First Known Use

1894, in the meaning defined above

Time Traveler
The first known use of antibody was in 1894

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Cite this Entry

“Antibody.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antibody. Accessed 2 Apr. 2026.

Kids Definition

antibody

noun
an·​ti·​body ˈant-i-ˌbäd-ē How to pronounce antibody (audio)
: a substance produced by special cells of the body that combines with an antigen and counteracts its effects or those of the microscopic plant or animal on which the antigen may occur

Medical Definition

antibody

noun
an·​ti·​body ˈant-i-ˌbäd-ē How to pronounce antibody (audio)
plural antibodies
: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

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