anti-vaxxer

noun
an·ti-vax·xer | \ ˌan-tē-ˈvak-sər , ˌan-ˌtī- \
plural anti-vaxxers

Definition of anti-vaxxer 

: a person who opposes vaccination or laws that mandate vaccination As anti-vaxxers launch a campaign against a bill that would eliminate their ability to opt out of required shots, supporters of the proposal are delivering more than 21,000 petition signatures to the office of state Sen. Ben Allen … —Alexei Koseff

First Known Use of anti-vaxxer

2009, in the meaning defined above

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The first known use of anti-vaxxer was in 2009

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