: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

Examples of antibody in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
If the antibody can’t produce those results, all the troubleshooting will have been a waste of time and money. John Timmer, ArsTechnica, 25 Aug. 2026 But brain cancers are especially challenging to treat because many emerging therapies such as antibody-drug conjugates can’t pass through the blood-brain barrier. Isabella Backman, Hartford Courant, 24 Aug. 2026 Twist Bioscience, in South San Francisco, received 1,260 of them, grew them as antibody fusions in human cells instead, and ran them on a different sensor format entirely. Jon Markman, Forbes.com, 23 Aug. 2026 The antibody brings the chemo drug to a specific site—a cancer or tumor—by virtue of its interaction with a specific target that the antibody recognizes. Maggie Donahue, HEALTH, 20 Aug. 2026 See All Example Sentences for antibody

Word History

Etymology

anti- + body entry 1, after German Antikörper

First Known Use

1894, in the meaning defined above

Time Traveler
The first known use of antibody was in 1894

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Cite this Entry

“Antibody.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antibody. Accessed 26 Aug. 2026.

Kids Definition

: a substance produced by special cells of the body that combines with an antigen and counteracts its effects or those of the microscopic plant or animal on which the antigen may occur

Medical Definition

plural antibodies
: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

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