al·​lo·​ge·​ne·​ic | \ ˌa-lō-jə-ˈnē-ik How to pronounce allogeneic (audio) \
variants: or less commonly allogenic \ ˌa-​lō-​ˈje-​nik How to pronounce allogeneic (audio) \

Definition of allogeneic

1 usually allogeneic : involving, derived from, or being individuals of the same species that are sufficiently unlike genetically to interact antigenically allogeneic stem cells allogeneic marrow transplantation — compare syngeneic
2 allogenic : caused by the action or influence of abiotic environmental factors allogenic (disturbance) processes, such as flooding and sediment deposition patterns, in addition to wind events.— Brian Lockhart et al.

Examples of allogeneic in a Sentence

Recent Examples on the Web The rest get allogeneic transplants, where donors can include siblings or unrelated donors determined to be a match. Ron Winslow, WSJ, "New Promise for Bone-Marrow Transplants," 28 May 2018 The company is taking over Pfizer Inc.’s collaboration and license agreement with Cellectis to develop a series of allogeneic CAR-T therapies, including UCART19, a blood cancer drug in Phase I clinical trials. Brian Gormley, WSJ, "Former Kite Pharma Executives Raise $300 Million in New Gig," 3 Apr. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'allogeneic.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of allogeneic

1929, in the meaning defined at sense 2

History and Etymology for allogeneic

alteration of allogenic, from allo- + -genic

Note: The word allogenic as a term in genetics was introduced by the British immunologist Peter A. Gorer (1907-61) in the article "Transplantese," Annals of the New York Academy of Science, vol. 87, no. 1 (May, 1960), pp. 604-606. In a subsequent article (P. A. Gorer, et al., "Proposed revisions of 'Transplantese'," Nature, vol. 189, no. 4769 (March 25, 1961), pp. 1024-25), the suggestion is made that allogenic be changed to allogeneic to avoid confusion with allergenic. The later article also introduces syngeneic as a synonym for earlier isogenic.

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The first known use of allogeneic was in 1929

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Cite this Entry

“Allogeneic.” Dictionary, Merriam-Webster, Accessed 12 May. 2021.

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More Definitions for allogeneic


al·​lo·​ge·​ne·​ic | \ ˌal-ō-jə-ˈnē-ik How to pronounce allogeneic (audio) \
variants: also allogenic \ -​ˈjen-​ik How to pronounce allogeneic (audio) \

Medical Definition of allogeneic

: involving, derived from, or being individuals of the same species that are sufficiently unlike genetically to interact antigenically allogeneic skin grafts — compare syngeneic, xenogeneic

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