allogeneic

adjective

al·lo·ge·ne·ic ˌa-lō-jə-ˈnē-ik

variants or less commonly allogenic

ˌa-lō-ˈje-nik

usually allogeneic : involving, derived from, or being individuals of the same species that are sufficiently unlike genetically to interact antigenically

allogeneic stem cells

allogeneic marrow transplantation

compare syngeneic

allogenic : caused by the action or influence of abiotic environmental factors

… allogenic (disturbance) processes, such as flooding and sediment deposition patterns, in addition to wind events.—

Brian Lockhart et al.

Example Sentences

Recent Examples on the Web The advent of allogeneic approaches to CAR T therapy is on the rise as new techniques are developed to further translate the potential of CAR T in the clinic. —

Demaris Mills, Forbes, 10 Aug. 2022 Though more research is needed, this serves as an early proof of concept outlining some of the potential advantages of an allogeneic approach over autologous CAR T-cells. —

Demaris Mills, Forbes, 10 Aug. 2022 Autologous and allogeneic therapy are the future of drug development. —

John Cumbers, Forbes, 25 Jan. 2022 The rest get allogeneic transplants, where donors can include siblings or unrelated donors determined to be a match. —

Ron Winslow, WSJ, 28 May 2018 The company is taking over Pfizer Inc.’s collaboration and license agreement with Cellectis to develop a series of allogeneic CAR-T therapies, including UCART19, a blood cancer drug in Phase I clinical trials. —

Brian Gormley, WSJ, 3 Apr. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'allogeneic.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

Etymology

alteration of allogenic, from allo- + -genic

Note: The word allogenic as a term in genetics was introduced by the British immunologist Peter A. Gorer (1907-61) in the article "Transplantese," Annals of the New York Academy of Science, vol. 87, no. 1 (May, 1960), pp. 604-606. In a subsequent article (P. A. Gorer, et al., "Proposed revisions of 'Transplantese'," Nature, vol. 189, no. 4769 (March 25, 1961), pp. 1024-25), the suggestion is made that allogenic be changed to allogeneic to avoid confusion with allergenic. The later article also introduces syngeneic as a synonym for earlier isogenic.

First Known Use

1929, in the meaning defined at sense 2

Time Traveler

The first known use of allogeneic was in 1929

See more words from the same year