AIDS

noun

: a disease of the human immune system that is characterized cytologically especially by reduction in the numbers of CD4-bearing helper T cells to 20 percent or less of normal thereby rendering the subject highly vulnerable to life-threatening conditions (such as Pneumocystis carinii pneumonia) and to some (such as Kaposi's sarcoma) that become life-threatening and that is caused by infection with HIV commonly transmitted in infected blood especially during illicit intravenous drug use and in bodily secretions (such as semen) during sexual intercourse

Examples of AIDS in a Sentence

Recent Examples on the Web
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The rollout was supported by the United States President's Emergency Plan for AIDS Relief, or PEPFAR, in partnership with the Global Fund, raising questions about future deliveries under the program. Arkansas Online, 26 Feb. 2026 Since its creation in 1996, the Florida AIDS Drug Assistance Program has been funded through the Ryan White CARE Act, which Congress passed into law in 1990. Jonathan Appelbaum, Sun Sentinel, 25 Feb. 2026 The roll out was supported by the United States President’s Emergency Plan for AIDS Relief, or PEPFAR, in partnership with the Global Fund, raising questions about future deliveries under the program. ABC News, 25 Feb. 2026 About a week after the AIDS Healthcare Foundation’s lawsuit, the state started its regular process to change the program requirements. Romy Ellenbogen, Miami Herald, 25 Feb. 2026 See All Example Sentences for AIDS

Word History

Etymology

acquired immunodeficiency syndrome

First Known Use

1982, in the meaning defined above

Time Traveler
The first known use of AIDS was in 1982

Cite this Entry

“AIDS.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/AIDS. Accessed 27 Feb. 2026.

Kids Definition

AIDS

noun
: a serious disease of the human immune system marked by destruction of a large proportion of the helper T cells in the body due to infection by the HIV virus commonly transmitted especially in blood and semen

Medical Definition

AIDS

noun
: a disease of the human immune system that is characterized cytologically especially by a reduction in the numbers of CD4-bearing helper T cells to 20 percent or less of normal thereby rendering the subject highly vulnerable to life-threatening conditions (as Pneumocystis carinii pneumonia) and to some that become life threatening (as Kaposi's sarcoma) and that is caused by infection with HIV commonly transmitted in infected blood especially during illicit intravenous drug use and in bodily secretions (as semen) during sexual intercourse

called also acquired immune deficiency syndrome, acquired immunodeficiency syndrome

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